Transcription Factor

Accessions: UP00557A (UniPROBE 20160601), Q9SGJ6 (JASPAR 2024), T05451 (AthalianaCistrome v4_May2016)
Names: DDF2, DREB1E, DWARF AND DELAYED FLOWERING2, Dehydration-responsive element-binding protein 1E, DRE1E_ARATH, Protein DREB1E, AT1G63030, T05451;
Organisms: Arabidopsis lyrata, Arabidopsis thaliana
Libraries: UniPROBE 20160601 1, JASPAR 2024 2, AthalianaCistrome v4_May2016 3
1 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed]
2 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
3 O'Malley RC, Huang SS, Song L, Lewsey MG, Bartlett A, Nery JR, Galli M, Gallavotti A, Ecker JR. Cistrome and Epicistrome Features Shape the Regulatory DNA Landscape. Cell 165:1280-92 (2016). [Pubmed]
Uniprot: Q9SGJ6
Description: DWARF AND DELAYED FLOWERING2: Orthologous to Arabidopsis thaliana DDF2
Notes: ecotype:Col-0, experiment type: DAP-seq, family:AP2-EREBP
Length: 181
Pfam Domains: 29-78 AP2 domain
Sequence:
(in bold interface residues)
1 MENDDITVAEMKPKKRAGRRIFKETRHPIYRGVRRRDGDKWVCEVREPIHQRRVWLGTYP 60
61 TADMAARAHDVAVLALRGRSACLNFSDSAWRLPVPASTDPDTIRRTAAEAAEMFRPPEFS 120
121 TGITVLPSASEFDTSDEGVAGMMMRLAEEPLMSPPRSYIDMNTSVYVDEEMCYEDLSLWS 180
181 Y
Interface Residues: 16, 34, 36, 37, 38, 39, 41, 44, 46, 50, 52, 53, 55
3D-footprint Homologues: 5wx9_A, 7wq5_A, 1gcc_A, 7et4_D
Binding Motifs: UP00557A_1 kkkrvtsATGTCGrCraggrth
UP00557A_2 gkbrmwrATGTCGRCvmkgaty
UP00557A_3 tsdrgysATGTCGrCrasgkmr
UP00557A_4 kkkgsysATGTCGrYrakrwtm
UP00557A_5 dkykcwrATGTCGrYrrkrmth
UP00557A_6 tskrgysATGTCGrCrasgkwr
MA0978.1 ATGTCGGC
M0129 ygATGTCGrCrrmrr
Binding Sites: AATGTCGG
ACCGACAT
AGCCGACA
ATGTCGAC
ATGTCGGC
CACCGACA
CATGTCGG
CCGACATA
CCGACATC
CGCCGACA
CGTCGACA
CTGCCGAC
GCCGACAC
GGCCGACA
GGTCGACA
GTCGACAC
GTCGGCAA
TACCGACA
TGCCGACA
TGTCGACA
Publications: Lehti-Shiu MD, Uygun S, Moghe GD, Panchy N, Fang L, Hufnagel DE, Jasicki HL, Feig M, Shiu SH. Molecular Evidence for Functional Divergence and Decay of a Transcription Factor Derived from Whole-Genome Duplication in Arabidopsis thaliana. Plant Physiol 168:1717-34 (2015). [Pubmed]

Magome H, Yamaguchi S, Hanada A, Kamiya Y, Oda K. The DDF1 transcriptional activator upregulates expression of a gibberellin-deactivating gene, GA2ox7, under high-salinity stress in Arabidopsis. Plant J 56:613-26 (2008). [Pubmed]
Related annotations: PaperBLAST

Disclaimer and license

These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.