Transcription Factor

						

			
Accessions: WRKY18 (Athamap 20091028), WRKY18 (ArabidopsisPBM 20140210), Q9C5T4 (JASPAR 2024), T17824 (AthalianaCistrome v4_May2016)

			
Names: AtWRKY18, WRKY DNA-binding protein 18, WRKY transcription factor 18, WRKY18, WRK18_ARATH, AT4G31800, T17824;
Organisms: Arabidopsis thaliana
Libraries: Athamap 20091028 1, ArabidopsisPBM 20140210 2, JASPAR 2024 3, AthalianaCistrome v4_May2016 4
1 Bulow L, Engelmann S, Schindler M, Hehl R. AthaMap, integrating transcriptional and post-transcriptional data. Nucleic acids research 37:D983-6 (2009).  [Pubmed]

2 Franco-Zorrilla J.M, López-Vidriero I, Carrasco J.L, Godoy M, Vera P, Solano R. DNA-binding specificities of plant transcription factors and their potential to define target genes. Proceedings of the National Academy of Sciences of the United States of America : (2014). [Pubmed]

3 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]

4 O'Malley RC, Huang SS, Song L, Lewsey MG, Bartlett A, Nery JR, Galli M, Gallavotti A, Ecker JR. Cistrome and Epicistrome Features Shape the Regulatory DNA Landscape. Cell 165:1280-92 (2016). [Pubmed]
Uniprot: Q9C5T4
Notes: WRKY, ecotype:Col-0, experiment type: ampDAP-seq, experiment type: ampDAP-seq (methyl-cytosines removed by PCR), experiment type: DAP-seq, family:WRKY
Length: 310
Pfam Domains:   175-233 WRKY DNA -binding domain
Sequence: 
(in bold interface residues)		   1 MDGSSFLDISLDLNTNPFSAKLPKKEVSVLASTHLKRKWLEQDESASELREELNRVNSEN   60
  61 KKLTEMLARVCESYNELHNHLEKLQSRQSPEIEQTDIPIKKRKQDPDEFLGFPIGLSSGK  120
 121 TENSSSNEDHHHHHQQHEQKNQLLSCKRPVTDSFNKAKVSTVYVPTETSDTSLTVKDGFQ  180
 181 WRKYGQKVTRDNPSPRAYFRCSFAPSCPVKKKVQRSAEDPSLLVATYEGTHNHLGPNASE  240
 241 GDATSQGGSSTVTLDLVNGCHRLALEKNERDNTMQEVLIQQMASSLTKDSKFTAALAAAI  300
 301 SGRLMEQSRT
Interface Residues: 182, 183, 184, 186, 187, 198
3D-footprint Homologues: 6j4g_B, 6ir8_A, 6j4e_B, 6j4f_F, 7z0u_A
Binding Motifs: WRKY18 rGTCAAmG
WRKY18 wcGGTCAAgs
MA1077.1 mhrGTCAAss
M0795 maarGTCAAsr
M0801 ygTTGACTtttty
MA1077.2 rGTCAA
Binding Sites: WRKY18_1
WRKY18_2
WRKY18_3
WRKY18_4
WRKY18_5
MA1077.1.7
MA1077.1.1
MA1077.1.10
MA1077.1.11
MA1077.1.12
MA1077.1.13
MA1077.1.14
MA1077.1.15
MA1077.1.16
MA1077.1.17
MA1077.1.18
MA1077.1.19
MA1077.1.2
MA1077.1.20
MA1077.1.3
MA1077.1.4
MA1077.1.5
MA1077.1.6
MA1077.1.8
MA1077.1.9
MA1077.2.20
MA1077.2.1
MA1077.2.10
MA1077.2.11
MA1077.2.12
MA1077.2.13
MA1077.2.14
MA1077.2.15
MA1077.2.16
MA1077.2.17
MA1077.2.18
MA1077.2.19
MA1077.2.2
MA1077.2.3
MA1077.2.4
MA1077.2.5
MA1077.2.6
MA1077.2.7
MA1077.2.8
MA1077.2.9
			
Publications: Du L, Chen Z. 2000. Identification of genes encoding receptor-like protein kinases as possible targets of pathogen- and salicylic acid-induced WRKY DNA-binding proteins in Arabidopsis. Plant J. 24:837-47. [Pubmed]


 Yu D, Chen C, Chen Z. 2001. Evidence for an important role of WRKY DNA binding proteins in the regulation of NPR1 gene expression. Plant Cell. 13:1527-40. [Pubmed]


 Chen C, Chen Z. 2002. Potentiation of developmentally regulated plant defense response by AtWRKY18, a pathogen-induced Arabidopsis transcription factor. Plant Physiol. 129:706-16. [Pubmed]


 Xu X, Chen C, Fan B, Chen Z. 2006. Physical and functional interactions between pathogen-induced Arabidopsis WRKY18, WRKY40, and WRKY60 transcription factors. Plant Cell 18: 1310-26. [Pubmed]
Related annotations: PaperBLAST

	
			


			

				

				
				
				
				

			

			

		

	
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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.