Transcription Factor

Accessions: UP00467A (UniPROBE 20160601)
Names: Ste12, STErile
Organisms: Saccharomyces cerevisiae
Libraries: UniPROBE 20160601 1
1 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed]
Description: STErile: Transcription factor that is activated by a MAP kinase signaling cascade, activates genes involved in mating or pseudohyphal/invasive growth pathways; cooperates with Tec1p transcription factor to regulate genes specific for invasive growth
Length: 210
Pfam Domains: 50-160 STE like transcription factor
Sequence:
(in bold interface residues)
1 SRTEEILKVQANNENDEVSKATPGEVEESLRLIGDLKFFLATAPVNWQENQIIRRYYLNS 60
61 GQGFVSCVFWNNLYYITGTDIVKCCLYRMQKFGREVVQKKKFEEGIFSDLRNLKCGIDAT 120
121 LEQPKSEFLSFLFRNMCLKTQKKQKVFFWFSVAHDKLFADALERDLKRESLNQPSTTKPV 180
181 NEPALSFSYDSSSDKPLYDQLLQHLDSRRP
Interface Residues: 54, 62, 72
3D-footprint Homologues: 6c1t_D, 2ky8_A
Binding Motifs: UP00467A_1 cmtdmmAbmTGAAACAwrrwgtw
Binding Sites: ATGAAACA
ACGTTTCA
ACTGAAAC
ATGAAACG
ATGTTTCA
CATGAAAC
CCTGAAAC
CGTTTCAG
CTGAAACA
CTGTTTCA
CTTGAAAC
GATGAAAC
GCGTTTCA
GCTGAAAC
GTGAAACA
GTGTTTCA
GTTTCAGA
GTTTCATA
TGAAACAA
TGTTTCAA
Publications: Gordân R, Murphy KF, McCord RP, Zhu C, Vedenko A, Bulyk ML. Curated collection of yeast transcription factor DNA binding specificity data reveals novel structural and gene regulatory insights. Genome Biol : (2011). [Pubmed]
Related annotations: PaperBLAST

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