Transcription Factor
| Accessions: | P22807 (JASPAR 2024) |
| Names: | Homeobox protein NK-1, Homeobox protein slou, Protein slouch, S59/2, SLOU_DROME |
| Organisms: | Drosophila melanogaster |
| Libraries: | JASPAR 2024 1 1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] |
| Length: | 659 |
| Pfam Domains: | 546-602 Homeobox domain |
| Sequence: (in bold interface residues) | 1 MVMLQSPAQKASDSASAQNTAVGGLMSPNSNPDSPKSNTSPDVASADSVVSGTGGGSTPP 60 61 AAKIPKFIISANGAAVAGKQEQELRYSLERLKQMSSESGSLLSRLSPLQEDSQDKEKPNH 120 121 NNNNSLTNHNANSNTRRSQSPPASVGSVSFSSPAQQRKLLELNAVRHLARPEPLQHPHAA 180 181 LLQQHPHLLQNPQFLAAAQQHMHHHQHQHHQHPAHPHSHQHPHPHPHPHPHPHPSAVFHL 240 241 RAPSSSSTAPPSPATSPLSPPTSPAMHSDQQMSPPIAPPQNPPHSSQPPQQQQVAAPSDM 300 301 DLERIKLVAAVAARTTQASSTSALASASNSVSNASISISNSSSGSPSGRDLSDYGFRIQL 360 361 GGLAAAAAAAAATSRQIAAATYARSDTSEELNVDGNDEDSNDGSHSTPSVCPVDLTRSVN 420 421 SSAAANPSSASTSASSDRDAATKRLAFSVENILDPNKFTGNKLPSGPFGHPRQWSYERDE 480 481 EMQERLDDDQSEDMSAQDLNDMDQDDMCDDGSDIDDPSSETDSKKGGSRNGDGKSGGGGG 540 541 GGSKPRRARTAFTYEQLVSLENKFKTTRYLSVCERLNLALSLSLTETQVKIWFQNRRTKW 600 601 KKQNPGMDVNSPTIPPPGGGSFGPGAYASGLLYSHAVPYPPYGPYFHPLGAHHLSHSHS |
| Interface Residues: | 546, 547, 548, 549, 550, 587, 588, 590, 591, 594, 595, 598, 599, 602 |
| 3D-footprint Homologues: | 2h1k_B, 1puf_A, 3cmy_A, 5zfz_A, 3d1n_M, 1fjl_B, 1ig7_A, 6a8r_A, 3lnq_A, 2lkx_A, 1jgg_B, 1mnm_C, 6m3d_C, 1nk2_P, 1zq3_P, 7q3o_C, 6es3_K, 2ld5_A, 3a01_E, 5jlw_D, 4xrs_G, 2hdd_A, 3rkq_B, 2r5y_A, 1puf_B, 1au7_A, 5flv_I, 2hos_A, 5zjt_E, 4cyc_A, 7psx_B, 1b72_A, 5hod_A, 3l1p_A, 7xrc_C, 1e3o_C, 2xsd_C, 1le8_A, 1le8_B, 1du0_A, 1k61_B, 8g87_X, 1o4x_A, 4qtr_D |
| Binding Motifs: | MA0245.1 tTAATtr |
| Binding Sites: | MA0245.1.2 MA0245.1.18 MA0245.1.16 MA0245.1.7 MA0245.1.14 MA0245.1.12 MA0245.1.11 MA0245.1.1 MA0245.1.10 MA0245.1.13 MA0245.1.15 MA0245.1.17 MA0245.1.19 MA0245.1.20 MA0245.1.3 MA0245.1.4 MA0245.1.5 MA0245.1.6 MA0245.1.8 MA0245.1.9 |
| Publications: | Noyes M.B, Meng X, Wakabayashi A, Sinha S, Brodsky M.H, Wolfe S.A. A systematic characterization of factors that regulate Drosophila segmentation via a bacterial one-hybrid system. Nucleic acids research 36:2547-60 (2008). [Pubmed] |
| Related annotations: | PaperBLAST |
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