Transcription Factor

						

			
Accessions: T057721_1.02 (CISBP 1.02)

			
Names: D19A, T057721_1.02;
Organisms: Drosophila melanogaster
Libraries: CISBP 1.02 1
1 Weirauch MT, Yang A, Albu M, Cote AG, Montenegro-Montero A, Drewe P, Najafabadi HS, Lambert SA, Mann I, Cook K, Zheng H, Goity A, van Bakel H, Lozano JC, Galli M, Lewsey MG, Huang E, Mukherjee T, Chen X, Reece-Hoyes JS, Govindarajan S, Shaulsky G, et al. Determination and inference of eukaryotic transcription factor sequence specificity. Cell. 2014 Sep 11;158(6):1431-43. doi: 10.1016/j.cell.2014.08.009. [Pubmed]
Notes: experiment type:B1H, family:C2H2 ZF
Length: 845
Pfam Domains:     12-82 Zinc-finger associated domain (zf-AD)  
  306-328 C2H2-type zinc finger
  339-363 C2H2-type zinc finger
  375-397 C2H2-type zinc finger
  389-414 Zinc-finger double domain
  404-426 C2H2-type zinc finger
  404-426 Zinc finger, C2H2 type
  432-454 C2H2-type zinc finger
  448-468 Zinc-finger double domain
  474-499 Zinc-finger double domain
  489-511 C2H2-type zinc finger
  518-539 C2H2-type zinc finger
  650-670 C2H2-type zinc finger
  694-717 Zinc-finger double domain
  707-727 Zinc-finger of C2H2 type
  707-729 C2H2-type zinc finger
  707-729 Zinc finger, C2H2 type
Sequence: 
(in bold interface residues)		   1 MNEGRQYSIHSLCRICLNHLQNDAAYDLYLVPGLSKKLCFCTSLSVEQNDGFPKNLCTLC   60
  61 YTKLNELHDFQKQCVDSVQKFQDLVASNVFACQSSFDVFDPNVAVQDYPAEEEDHVNYDP  120
 121 LLNHKMELIENEEDVFKMLEHVDKEAEEVEKEAKVEEDDGGNVSVKMFDDDSSIESGNDN  180
 181 DHDLDFEPNSSDDDIPLAQRMRGPATGSGPQQDRFSNLDKPKPRPRGRPKKIKPPPPEEE  240
 241 ELSDSSSESDDSEDGTSRGDKPKRKRIPIEERHLHRIIDCHICHQKFKKAIRYEEHMKYH  300
 301 NDLLPFQCKVETCKKGFTTANGLRIHIDHAHTELSEVHACIAEGCGKTFPRVRLLTFHMK  360
 361 KVHGITKAAAPLRDFPCTECDTVFRCPTALKKHMYKHTGEELPYPCNICGKRFVINSALR  420
 421 DHLMRHAGIKNHVCPYCGVGKTTRQEWNAHILTHTKEKKFKCRQCDHASHNKQALSNHVK  480
 481 VVHEKRKDFACQYCGKTFGKSHACKVHERSHTGEKCCECKICGKIFLCEKSLTKHLKTHE  540
 541 KRDLPPAEPLRQQLNIPMPGQMSVPMPGQMPMQMQTDGLVPMDPNQMPSEDMLKACGGGT  600
 601 AAVPPKPKNSRRVQRVDISQLAGTAVNPIPSVSVPSWSPQVNFTKKEGQHICPGCGRGFN  660
 661 NIGNMKLHYKIIHEKVKDFACRFCPKRFSKAQILRHHEWIHTGEKPFECKICGKHFRQET  720
 721 ALKKHIKTHEKPNRRHVPERSAPTQITFRKLEPDAEPRNFDQYQDPAVERAAATAELLAH  780
 781 QLEENEAKRKAEIERQKIAAAACEQLTKLQQQQEIIKATTSYDGYYAQKAQSEGTSLDAL  840
 841 KIDHV
Interface Residues: 288, 289, 291, 292, 319, 321, 322, 328, 350, 351, 352, 353, 354, 357, 361, 385, 386, 387, 388, 389, 392, 414, 415, 416, 417, 418, 420, 421, 425, 442, 443, 444, 445, 446, 449, 452, 471, 472, 473, 474, 476, 477, 500, 502, 503, 506, 528, 530, 531, 532, 534, 558, 561, 564, 614, 615, 616, 617, 632, 635, 660, 661, 662, 663, 664, 666, 667, 669, 670, 671, 674, 688, 689, 690, 691, 692, 693, 695, 696, 697, 700, 717, 718, 719, 720, 721, 722, 723, 724, 725
3D-footprint Homologues: 1tf3_A, 1tf6_A, 5v3j_F, 6a57_A, 7n5w_A, 5k5i_A, 8ssu_A, 5ei9_F, 8h9h_G, 7y3m_I, 8ssq_A, 7w1m_H, 6e94_A, 7txc_E, 6ml4_A, 5yel_A, 5yj3_D, 5k5l_F, 6u9q_A, 6jnm_A, 1g2f_F, 5kl3_A, 1ubd_C, 2kmk_A, 7ysf_A, 2drp_D, 6blw_A, 4x9j_A, 2gli_A, 5kkq_D, 2lt7_A, 2jpa_A, 3uk3_C, 8cuc_F, 7y3l_A, 1llm_D, 1f2i_J, 2wbs_A, 8gn3_A, 4m9v_C
Binding Motifs: M4901_1.02 TGTGAATGA
			
Related annotations: PaperBLAST

	
			


			

				

				
				
				
				

			

			

		

	
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