Transcription Factor

						

			
Accessions: USF1_DBD (HumanTF 1.0)

			
Names: bHLHb11, Class B basic helix-loop-helix protein 11, Major late transcription factor 1, Upstream stimulatory factor 1, USF1, USF1_HUMAN
Organisms: Homo sapiens
Libraries: HumanTF 1.0 1
1 Jolma A, Yan J, Whitington T, Toivonen J, Nitta KR, Rastas P, Morgunova E, Enge M, Taipale M, Wei G, Palin K, Vaquerizas JM, Vincentelli R, Luscombe NM, Hughes TR, Lemaire P, Ukkonen E, Kivioja T, Taipale J. DNA-Binding Specificities of Human Transcription Factors. Cell. 2013 Jan 17;152(1-2):327-39. [Pubmed]
Uniprot: P22415
Notes: Ensembl ID: ENSG00000158773; DNA-binding domain sequence; TF family: bHLH; Clone source: Gene synthesis
Length: 123
Pfam Domains:     21-75 Helix-loop-helix DNA-binding domain
Sequence: 
(in bold interface residues)		   1 PRTHPYSPKSEAPRTTRDEKRRAQHNEVERRRRDKINNWIVQLSKIIPDCSMESTKSGQS   60
  61 KGGILSKACDYIQELRQSNHRLSEELQGLDQLQLDNDVLRQQVEDLKNKNLLLRAQLRHH  120
 121 GLE
Interface Residues: 22, 24, 25, 26, 28, 29, 32, 33, 59, 61
3D-footprint Homologues: 1a0a_B, 1an4_A, 5v0l_A, 7rcu_E, 5gnj_I, 6g1l_A, 4h10_A, 7ssa_L, 5i50_B, 1am9_A, 7d8t_A, 4zpk_A, 7xi3_A, 5nj8_D, 7f2f_B, 5eyo_A, 8osl_P, 2ypa_B
Binding Motifs: USF1_DBD rtCACGTGay
			
Publications: Jolma A, Yan J, Whitington T, Toivonen J, Nitta KR, Rastas P, Morgunova E, Enge M, Taipale M, Wei G, Palin K, Vaquerizas JM, Vincentelli R, Luscombe NM, Hughes TR, Lemaire P, Ukkonen E, Kivioja T, Taipale J. DNA-Binding Specificities of Human Transcription Factors. Cell. 2013 Jan 17;152(1-2):327-39. [Pubmed]
Related annotations: PaperBLAST

	
			


			

				

				
				
				
				

			

			

		

	
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