Transcription Factor

Accessions: 1nwq_A (3D-footprint 20231221), 1nwq_C (3D-footprint 20231221)
Names: C/EBP alpha, CCAAT/enhancer binding protein alpha, CCAAT/enhancer-binding protein alpha, CEBPA_RAT
Organisms: Rattus norvegicus
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Uniprot: P05554
Length: 60
Pfam Domains: 2-54 Basic region leucine zipper
7-58 bZIP transcription factor
Sequence:
(in bold interface residues)
1 NSNEYRVRRERNNIAVRKSRDKAKQRNVETQQKVLELTSDNDRLRKRVEQLSRELDTLRG 60
Interface Residues: 8, 9, 12, 13, 15, 16, 19, 20
3D-footprint Homologues: 2wt7_A, 1nwq_C, 6mg1_B, 5t01_B, 2c9l_Z, 2dgc_A
Binding Motifs: 1nwq_AC TTGCGCAA
1nwq_C TTGC
Binding Sites: 1nwq_B
1nwq_D
Publications: Miller M, Shuman J.D, Sebastian T, Dauter Z, Johnson P.F. Structural basis for DNA recognition by the basic region leucine zipper transcription factor CCAAT/enhancer-binding protein alpha. The Journal of biological chemistry 278:15178-84 (2003). [Pubmed]
Related annotations: PaperBLAST

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