Transcription Factor

Accessions: Q5JT82 (JASPAR 2024)
Names: KLF17_HUMAN, Krueppel-like factor 17, Zinc finger protein 393
Organisms: Homo sapiens
Libraries: JASPAR 2024 1
1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Length: 389
Pfam Domains: 283-307 C2H2-type zinc finger
283-307 Zinc finger, C2H2 type
299-320 Zinc-finger double domain
313-337 C2H2-type zinc finger
313-337 Zinc finger, C2H2 type
330-352 Zinc-finger double domain
343-365 C2H2-type zinc finger
343-365 Zinc finger, C2H2 type
Sequence:
(in bold interface residues)
1 MYGRPQAEMEQEAGELSRWQAAHQAAQDNENSAPILNMSSSSGSSGVHTSWNQGLPSIQH 60
61 FPHSAEMLGSPLVSVEAPGQNVNEGGPQFSMPLPERGMSYCPQATLTPSRMIYCQRMSPP 120
121 QQEMTIFSGPQLMPVGEPNIPRVARPFGGNLRMPPNGLPVSASTGIPIMSHTGNPPVPYP 180
181 GLSTVPSDETLLGPTVPSTEAQAVLPSMAQMLPPQDAHDLGMPPAESQSLLVLGSQDSLV 240
241 SQPDSQEGPFLPEQPGPAPQTVEKNSRPQEGTGRRGSSEARPYCCNYENCGKAYTKRSHL 300
301 VSHQRKHTGERPYSCNWESCSWSFFRSDELRRHMRVHTRYRPYKCDQCSREFMRSDHLKQ 360
361 HQKTHRPGPSDPQANNNNGEQDSPPAAGP
Interface Residues: 142, 188, 295, 296, 297, 298, 299, 301, 302, 303, 304, 305, 308, 325, 326, 327, 328, 329, 330, 331, 332, 333, 336, 353, 354, 355, 356, 357, 358, 359, 360
3D-footprint Homologues: 8e24_A, 7y3l_A, 6ml4_A, 7n5w_A, 3uk3_C, 1tf3_A, 6jnm_A, 8cuc_F, 8ssq_A, 1tf6_A, 5v3j_F, 4x9j_A, 2i13_A, 6blw_A, 5kkq_D, 8ssu_A, 1ubd_C, 6u9q_A, 5ei9_F, 1mey_C, 5kl3_A, 7ysf_A, 6wmi_A, 2kmk_A, 7w1m_H, 5und_A, 2gli_A, 1g2f_F, 7eyi_G, 8h9h_G, 4m9v_C, 2lt7_A, 7y3m_I, 6e94_A, 6a57_A, 2jpa_A, 5k5l_F, 1llm_D, 2wbs_A, 5yel_A, 8gn3_A, 7txc_E, 2drp_D, 1f2i_J, 5yj3_D, 5k5i_A
Binding Motifs: MA1514.1 mmCCACgCaCCCmty
MA1514.2 mCCACgCaCCCmty
Publications: Bieker JJ. Krüppel-like factors: three fingers in many pies. J Biol Chem 276:34355-8 (2001). [Pubmed]
Related annotations: PaperBLAST

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