Transcription Factor
| Accessions: | UP00068A (UniPROBE 20160601) |
| Names: | C77258, Eomes, Eomesodermin homolog (Xenopus laevis), Tbr2 |
| Organisms: | Mus musculus |
| Libraries: | UniPROBE 20160601 1 1 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed] |
| Uniprot: | O54839 |
| Description: | Eomesodermin homolog (Xenopus laevis): Mus musculus similar to Eomesodermin homolog (LOC235673), mRNA |
| Length: | 245 |
| Pfam Domains: | 19-207 T-box |
| Sequence: (in bold interface residues) | 1 SCGGLGGLGVPGSGFRAHVYLCNRPLWLKFHRHQTEMIITKQGRRMFPFLSFNINGLNPT 60 61 AHYNVFVEVVLADPNHWRFQGGKWVTCGKADNNMQGNRMYVHPESPNTGSHWMRQEISFG 120 121 KLKLTNNKGANNNNTQMIVLQSLHKYQPRLHIVEVTEDGVEDLNEPSKTQTFTFSETQFI 180 181 AVTAYQNTDITQLKIDHNPFAKGFRDNYDSMYTASENDRLTPSPTDSPRSHQIVPGGRYG 240 241 VQNFF |
| Interface Residues: | 44, 183, 184, 200, 203, 204 |
| 3D-footprint Homologues: | 6f59_B, 2x6v_A, 4a04_B, 1h6f_B, 5flv_I, 1xbr_B |
| Binding Motifs: | UP00068A_1 krwarGGTGTGAAawyy UP00068A_2 vsrgAGGTGTyGscys |
| Binding Sites: | AAGTGTGA AGGTGAGA AGGTGCGA AGGTGTCA AGGTGTCG AGGTGTGA AGGTGTTA AGTGTGAA ATCACACC ATGTGTGA CTTCACAC GGGTGTGA GGTGCGAA GGTGTGAC GGTGTTAA GGTGTTAC GTGTGAAA GTGTGAAC TCACACCA ATTCACAC |
| Publications: | Badis G, Berger M.F, Philippakis A.A, Talukder S, Gehrke A.R, Jaeger S.A, Chan E.T, Metzler G, Vedenko A, Chen X, Kuznetsov H, Wang C.F, Coburn D, Newburger D.E, Morris Q, Hughes T.R, Bulyk M.L. Diversity and complexity in DNA recognition by transcription factors. Science (New York, N.Y.) 324:1720-3 (2009). [Pubmed] |
| Related annotations: | PaperBLAST |
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