Transcription Factor
| Accessions: | UP00064A (UniPROBE 20160601) |
| Names: | AI385749, Ra, Ragl, Sox-18, Sox18, SRY-box containing gene 18, Sry-related HMG-box gene, Transcription factor SOX-18 |
| Organisms: | Mus musculus |
| Libraries: | UniPROBE 20160601 1 1 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed] |
| Uniprot: | P43680 |
| Description: | SRY-box containing gene 18 |
| Length: | 101 |
| Pfam Domains: | 17-85 HMG (high mobility group) box 18-78 Domain of unknown function (DUF1898) |
| Sequence: (in bold interface residues) | 1 RYGFGRGERQTADELRIRRPMNAFMVWAKDERKRLAQQNPDLHNAVLSKMLGKAWKELNT 60 61 AEKRPFVEEAERLRVQHLRDHPNYKYRPRRKKQERKVRRLE |
| Interface Residues: | 19, 22, 24, 25, 28, 32, 43, 44, 45, 48, 86, 90 |
| 3D-footprint Homologues: | 3u2b_C, 1o4x_B, 7m5w_A, 3f27_D, 4s2q_D, 1qrv_A, 3tmm_A, 4y60_C, 2gzk_A, 1j5n_A, 6jrp_D, 2lef_A, 1hry_A, 3tq6_B |
| Binding Motifs: | UP00064A_1 twyhATTGTTbtmamw UP00064A_2 gkrsyraATtyrwdhm |
| Binding Sites: | ATTATAAT AAAACAAT AAACAATT AACAATAA AACAATAG AACAATTA AACAATTG AATTCAAT AATTGTTA ACAACAAT ACAATTAA ACAATTGT AGAACAAT AGACAATA ATTGTTAA ATTGTTCA ATTGTTTC CATTGTTA GAACAATA TAACAATA |
| Publications: | Badis G, Berger M.F, Philippakis A.A, Talukder S, Gehrke A.R, Jaeger S.A, Chan E.T, Metzler G, Vedenko A, Chen X, Kuznetsov H, Wang C.F, Coburn D, Newburger D.E, Morris Q, Hughes T.R, Bulyk M.L. Diversity and complexity in DNA recognition by transcription factors. Science (New York, N.Y.) 324:1720-3 (2009). [Pubmed] |
| Related annotations: | PaperBLAST |
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