Transcription Factor
| Accessions: | IRF1_MOUSE (HOCOMOCO 10), P15314 (JASPAR 2024) |
| Names: | Interferon regulatory factor 1, IRF-1, IRF1_MOUSE |
| Organisms: | Mus musculus |
| Libraries: | HOCOMOCO 10 1, JASPAR 2024 2 1 Kulakovskiy IV, Vorontsov IE, Yevshin IS, Soboleva AV, Kasianov AS, Ashoor H, Ba-Alawi W, Bajic VB, Medvedeva YA, Kolpakov FA, Makeev VJ. HOCOMOCO: expansion and enhancement of the collection of transcription factor binding sites models. Nucleic Acids Res : (2016). [Pubmed] 2 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] |
| Length: | 329 |
| Pfam Domains: | 5-113 Interferon regulatory factor transcription factor |
| Sequence: (in bold interface residues) | 1 MPITRMRMRPWLEMQINSNQIPGLIWINKEEMIFQIPWKHAAKHGWDINKDACLFRSWAI 60 61 HTGRYKAGEKEPDPKTWKANFRCAMNSLPDIEEVKDQSRNKGSSAVRVYRMLPPLTRNQR 120 121 KERKSKSSRDTKSKTKRKLCGDVSPDTFSDGLSSSTLPDDHSSYTTQGYLGQDLDMERDI 180 181 TPALSPCVVSSSLSEWHMQMDIIPDSTTDLYNLQVSPMPSTSEAATDEDEEGKIAEDLMK 240 241 LFEQSEWQPTHIDGKGYLLNEPGTQLSSVYGDFSCKEEPEIDSPRGDIGIGIQHVFTEMK 300 301 NMDSIMWMDSLLGNSVRLPPSIQAIPCAP |
| Interface Residues: | 40, 41, 42, 50, 75, 79, 80, 82, 83, 84, 86, 87, 89, 90 |
| 3D-footprint Homologues: | 2pi0_B, 1if1_B, 2o61_A, 8hcm_A, 8sfh_A, 2irf_L, 7oot_B, 8hcl_A |
| Binding Motifs: | IRF1_MOUSE.H10MO.C|M01171 rAAAsyGAAAsy MA0050.3 amtGAAAcTGAAAsy MA0050.4 tGAAAcTGAAA |
| Binding Sites: | MA0050.3.1 MA0050.3.10 MA0050.3.11 MA0050.3.12 MA0050.3.13 MA0050.3.14 MA0050.3.15 MA0050.3.16 MA0050.3.17 MA0050.3.18 MA0050.3.19 MA0050.3.2 / MA0050.3.5 MA0050.3.20 MA0050.3.3 / MA0050.3.7 MA0050.3.4 MA0050.3.10 / MA0050.3.5 MA0050.3.13 / MA0050.3.6 MA0050.3.15 / MA0050.3.7 MA0050.3.16 / MA0050.3.8 MA0050.3.9 MA0050.3.11 MA0050.3.12 MA0050.3.14 MA0050.3.17 MA0050.3.18 MA0050.3.19 MA0050.3.2 MA0050.3.20 MA0050.3.3 MA0050.3.4 MA0050.3.6 MA0050.3.8 MA0050.3.9 MA0050.4.1 MA0050.4.10 MA0050.4.11 MA0050.4.12 MA0050.4.13 MA0050.4.14 MA0050.4.15 MA0050.4.16 MA0050.4.17 MA0050.4.18 MA0050.4.19 MA0050.4.2 MA0050.4.20 / MA0050.4.6 MA0050.4.3 MA0050.4.4 MA0050.4.5 MA0050.4.7 MA0050.4.8 MA0050.4.9 |
| Publications: | Shi L, Perin J.C, Leipzig J, Zhang Z, Sullivan K.E. Genome-wide analysis of interferon regulatory factor I binding in primary human monocytes. Gene 487:21-8 (2011). [Pubmed] |
| Related annotations: | PaperBLAST |
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