Transcription Factor

						

			
Accessions: T074602_1.02 (CISBP 1.02)

			
Names: Mbd1, T074602_1.02;
Organisms: Mus musculus
Libraries: CISBP 1.02 1
1 Weirauch MT, Yang A, Albu M, Cote AG, Montenegro-Montero A, Drewe P, Najafabadi HS, Lambert SA, Mann I, Cook K, Zheng H, Goity A, van Bakel H, Lozano JC, Galli M, Lewsey MG, Huang E, Mukherjee T, Chen X, Reece-Hoyes JS, Govindarajan S, Shaulsky G, et al. Determination and inference of eukaryotic transcription factor sequence specificity. Cell. 2014 Sep 11;158(6):1431-43. doi: 10.1016/j.cell.2014.08.009. [Pubmed]
Notes: experiment type:PBM, family:CxxC
Length: 577
Pfam Domains:      3-69 Methyl-CpG binding domain
  195-241 CXXC zinc finger domain
  244-288 CXXC zinc finger domain
Sequence: 
(in bold interface residues)		   1 MAESWQDCPALGPGWKRRESFRKSGASFGRSDIYYQSPTGEKIRSKVELTRYLGPACDLT   60
  61 LFDFRQGTLCHPIPKTHPLAVPSKKKKKPSKPAKTKKQQVGLQRSEVRRETPQGEYKAPT  120
 121 ATALASLSVSASASSSASASASSSASASASASSHAPVCCENCGIHFSWDGVKRQRLKTLC  180
 181 KDCRAQRIAFNREQRMFKRVGCGDCAACLVKEDCGVCSTCRLQLPSDVASGLYCKCERRR  240
 241 CLRIMEKSRGCGVCRGCQTQEDCGHCCICLRSPRPGLKRQWRCLQRRCFWGKRDSSKRGS  300
 301 KVASQRHSQAPPLPPHPASQYTEPTELHISDIAPTSPAEFIYYCVDEDEDELKRLLPSAG  360
 361 SGSGEGAGLRPYQTHQTHQKRPASARQLQLSSPLKAPWAVVTAPPGPVRDSRKQQAGRGS  420
 421 VLPQPDTDFVFLQEGTSSAMQMPGTAAACTEVPVQAAQCSAPSWVVALPQVKQETADAPE  480
 481 EWTAVTTFLTSSTLQSGFPSKAADPDLSPVKQEPPGPEEDGEEKKDDVSETTPAEEIGGV  540
 541 GTPVITEIFSLGGTRLRDAEAWLPRSKDLKNPEAKMQ
Interface Residues: 22, 26, 27, 30, 32, 34, 42, 44, 277, 280, 281, 293, 296
3D-footprint Homologues: 6ogk_A, 3vxv_A, 2ky8_A, 6c1t_D, 2moe_A, 6ceu_B, 3qmd_A
Binding Motifs: M0613_1.02 CGCGCGaT
			
Related annotations: PaperBLAST

	
			


			

				

				
				
				
				

			

			

		

	
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