Transcription Factor

Accessions: 3q5f_A (3D-footprint 20231221)
Names: Cytolysin SlyA, Salmolysin, SLYA_SALTY, Transcriptional regulator slyA
Organisms: Salmonella enterica subsp. enterica serovar Typhimurium, strain LT2 / SGSC1412 / ATCC 700720
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Uniprot: P40676
Length: 141
Pfam Domains: 27-86 MarR family
28-94 Winged helix DNA-binding domain
28-86 MarR family
Sequence:
(in bold interface residues)
1 ESPLGSDLARLVRIWRALIDHRLKPLELTQTHWVTLHNIHQLPPDQSQIQLAKAIGIEQP 60
61 SLVRTLDQLEDKGLISRQTCASDRRAKRIKLTEKAEPLIAEMEEVIHKTRGEILAGISSE 120
121 EIELLIKLIAKLEHNIMELHS
Interface Residues: 48, 58, 59, 60, 61, 63, 64, 65, 67, 68, 85
3D-footprint Homologues: 7el3_B, 3iyd_H, 6jbx_A, 3q5f_A, 5yi2_J, 7bhy_A, 5h3r_A, 1z9c_A, 6c2s_C, 5hlg_E, 4fx4_B, 6q2b_B, 4kdp_B, 3zpl_B, 4aik_A, 5hso_A, 7dvv_A
Binding Motifs: 3q5f_A AGCTAAnnRT
3q5f_AB TAnntTAGCAAGCTAAnnAT
Binding Sites: 3q5f_C
3q5f_D
Publications: Dolan K.T, Duguid E.M, He C. Crystal structures of SlyA protein, a master virulence regulator of Salmonella, in free and DNA-bound states. The Journal of biological chemistry 286:22178-85 (2011). [Pubmed]
Related annotations: PaperBLAST

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