Transcription Factor

Accessions: 4wwc_B (3D-footprint 20231221)
Names: HTH-type transcriptional repressor NagR, HTH-type transcriptional repressor YvoA, N-acetylglucosamine utilization regulator, NAGR_BACSU
Organisms: Bacillus subtilis, strain 168
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Uniprot: O34817
Length: 231
Pfam Domains: 13-75 Bacterial regulatory proteins, gntR family
40-76 DeoR-like helix-turn-helix domain
93-224 UTRA domain
Sequence:
(in bold interface residues)
1 HMNINKQSPIPIYYQIMEQLKTQIKNGELQPDMPLPSEREYAEQFGISRMTVRQALSNLV 60
61 NEGLLYRLKGRGTFVSKPKMEQGLTSFTEDMKSRGMTPGSRLIDYQLIDSEELAAILGCG 120
121 PSSIHKITRVRLANDIPMAIESSHIPFELAGELNESIYDHIERYNSIPISRAKQELEPSA 180
181 ATTEEANILGIQKGAPVLLIKRTTYLQNGTAFEHAKSVYRGDRYTFVHYMD
Interface Residues: 13, 37, 38, 39, 42, 48, 49, 50, 51, 52, 53, 54, 57, 69, 70
3D-footprint Homologues: 7zla_B, 6wg7_G, 4h0e_A, 4wwc_B, 4p9u_F, 6za3_B, 4u0y_B, 1h9t_B, 4i2o_B, 3wgi_D
Binding Motifs: 4wwc_AB TGGTCTAnACCa
4wwc_B CrrnnnnnTAnACCa
Binding Sites: 4wwc_E / 4wwc_F
Publications: Fillenberg S.B, Grau F.C, Seidel G, Muller Y.A. Structural insight into operator dre-sites recognition and effector binding in the GntR/HutC transcription regulator NagR. Nucleic acids research 43:1283-96 (2015). [Pubmed]
Related annotations: PaperBLAST

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