Transcription Factor
| Accessions: | 3mfk_A (3D-footprint 20231221) |
| Names: | ETS1_HUMAN, p54, Protein C-ets-1 |
| Organisms: | Homo sapiens |
| Libraries: | 3D-footprint 20231221 1 1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed] |
| Uniprot: | P14921 |
| Length: | 138 |
| Pfam Domains: | 34-115 Ets-domain |
| Sequence: (in bold interface residues) | 1 GTFKDYVRDRADLNKDKPVIPAAALAGYTGSGPIQLWQFLLELLTDKSCQSFISWTGDGW 60 61 EFKLSDPDEVARRWGKRKNKPKMNYEKLSRGLRYYYDKNIIHKTAGKRYVYRFVCDLQSL 120 121 LGYTPEELHAMLDVKPDA |
| Interface Residues: | 31, 64, 68, 69, 72, 86, 87, 89, 90, 91, 93, 94, 108 |
| 3D-footprint Homologues: | 3zp5_A, 2wbs_A, 4uno_A, 3jtg_A, 7jsa_J, 2stt_A, 8ee9_F, 4mhg_A, 1dux_F, 4l18_B, 1yo5_C, 1awc_A, 4lg0_B, 4bqa_A, 1bc8_C, 4iri_A |
| Binding Motifs: | 3mfk_AB AGGAagnnnnTCC |
| Publications: | Babayeva N.D, Wilder P.J, Shiina M, Mino K, Desler M, Ogata K, Rizzino A, Tahirov T.H. Structural basis of Ets1 cooperative binding to palindromic sequences on stromelysin-1 promoter DNA. Cell cycle (Georgetown, Tex.) 9:3054-62 (2010). [Pubmed] |
| Related annotations: | PaperBLAST |
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