Transcription Factor

						

			
Accessions: Ttk (SMILE-seq 1.0)

			
Names: Protein tramtrack, beta isoform, Repressor protein fushi tarazu, Tramtrack p69, Ttk, TTKB_DROME
Organisms: Drosophila melanogaster
Libraries: SMILE-seq 1.0 1
1 Isakova A, Groux R, Imbeault M, Rainer P, Alpern D, Dainese R, Ambrosini G, Trono D, Bucher P, Deplancke B. SMiLE-seq identifies binding motifs of single and dimeric transcription factors. Nat Methods 14:316-322 (2017). [Pubmed]
Uniprot: P17789
Length: 642
Pfam Domains:    23-118 BTB/POZ domain
  538-561 Zinc finger, C2H2 type
Sequence: 
(in bold interface residues)		   1 MKMASQRFCLRWNNHQSNLLSVFDQLLHAETFTDVTLAVEGQHLKAHKMVLSACSPYFNT   60
  61 LFVSHPEKHPIVILKDVPYSDMKSLLDFMYRGEVSVDQERLTAFLRVAESLRIKGLTEVN  120
 121 DDKPSPAAAAAGAGATGSESTATTPQLQRIQPYLVPQRNRSQAGGLLASAANAGNTPTLP  180
 181 VQPSLLSSALMPKRKRGRPRKLSGSSNGTGNDYDDFDRENMMNDSSDLGNGKMCNESYSG  240
 241 NDDGSDDNQPNAGHTDDLNESRDSLPSKRSKNSKDHRVVSHHEDNSTSDGNDSDGEGLDT  300
 301 SYMEPQLMLDEYDEPVEFKYNPLTDNSSPTQDHTDGSHLNEQARQQAFLIAAQRKHQVET  360
 361 AAAAAASGIKLNIIGMAAGGAQVKSMVSIPKLTPIGKVNAASTPLVSPAGSFSTATVKPR  420
 421 VQKRPKLGKQNGDVKPAVFSSQEYLDIYNSNDGFKLKAAGLSGSTPNLSAGLGTPSVKTK  480
 481 LNLSSNVGEGEAEGSVRDYCTKEGEHTYRCKVCSRVYTHISNFCRHYVTSHKRNVKVYPC  540
 541 PFCFKEFTRKDNMTAHVKIIHKIENPSTALATVAAANLAGQPLGVSGASTPPPPDLSGQN  600
 601 SNQSLPATSNALSTSSSSSTSSSSGSLGPLTTSAPPAPAAAA
Interface Residues: 478, 481, 497, 503, 505, 506, 508, 518, 519, 520, 521, 522, 523, 524, 525, 526, 527, 530, 548, 549, 550, 551, 552, 554, 555, 558, 559
3D-footprint Homologues: 7w1m_H, 5und_A, 8ssq_A, 5kkq_D, 8ssu_A, 5ei9_F, 2lt7_A, 5yel_A, 2kmk_A, 1g2f_F, 7n5w_A, 1mey_C, 6blw_A, 1f2i_J, 6e94_A, 5k5i_A, 2i13_A, 2wbs_A, 8cuc_F, 6ml4_A, 2jpa_A, 2drp_D, 8gn3_A, 6u9q_A, 5kl3_A, 2gli_A, 8h9h_G, 7eyi_G, 1tf3_A, 7ysf_A, 1tf6_A, 1llm_D, 4x9j_A, 7txc_E, 5yj3_D
Binding Motifs: Ttk kmmAGGAyAh
			
Publications: Isakova A, Groux R, Imbeault M, Rainer P, Alpern D, Dainese R, Ambrosini G, Trono D, Bucher P, Deplancke B. SMiLE-seq identifies binding motifs of single and dimeric transcription factors. Nat Methods 14:316-322 (2017). [Pubmed]
Related annotations: PaperBLAST

	
			


			

				

				
				
				
				

			

			

		

	
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