Transcription Factor

Accessions: 4h10_A (3D-footprint 20231221)
Names: Aryl hydrocarbon receptor nuclear translocator-like protein 1, Basic-helix-loop-helix-PAS protein MOP3, bHLH-PAS protein JAP3, bHLHe5, BMAL1_HUMAN, Brain and muscle ARNT-like 1, Class E basic helix-loop-helix protein 5, Member of PAS protein 3, PAS domain-containing protein 3
Organisms: Homo sapiens
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Uniprot: O00327
Length: 60
Pfam Domains: 6-57 Helix-loop-helix DNA-binding domain
Sequence:
(in bold interface residues)
1 RIKNAREAHSQIEKRRRDKMNSFIDELASLVPTCNAMSRKLDKLTVLRMAVQHMKTLRGA 60
Interface Residues: 6, 8, 9, 10, 12, 13, 16, 17, 21, 41, 43
3D-footprint Homologues: 7z5k_B, 1a0a_B, 1an4_A, 4zpr_B, 1am9_A, 7ssa_L, 5nj8_D, 4h10_B, 7xq5_A, 6g1l_A, 5eyo_A, 5sy7_B, 4zpk_A, 7d8t_A, 5gnj_I, 7xi3_A, 5v0l_A, 8osl_O, 7f2f_B, 4h10_A, 8osl_P, 2ypa_A, 5nj8_C, 7xhv_B, 4zpk_B, 7xi3_B, 5v0l_B
Binding Motifs: 4h10_A TCAcg
4h10_AB TCACGtG
Binding Sites: 4h10_C
4h10_D
Publications: Wang Z, Wu Y, Li L, Su X.D. Intermolecular recognition revealed by the complex structure of human CLOCK-BMAL1 basic helix-loop-helix domains with E-box DNA. Cell research : (2012). [Pubmed]
Related annotations: PaperBLAST

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