Transcription Factor
| Accessions: | Q61080 (JASPAR 2024) |
| Names: | Forkhead box protein F1, Forkhead-related protein FKHL5, Forkhead-related transcription factor 1, FOXF1_MOUSE, FREAC-1, Hepatocyte nuclear factor 3 forkhead homolog 8, HFH-8 |
| Organisms: | Mus musculus |
| Libraries: | JASPAR 2024 1 1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] |
| Length: | 378 |
| Pfam Domains: | 48-140 Fork head domain |
| Sequence: (in bold interface residues) | 1 MSAPDKQQPPHGGGTGGGGGAGGQAMDPAAAGPTKAKKTNAGVRRPEKPPYSYIALIVMA 60 61 IQSSPSKRLTLSEIYQFLQARFPFFRGAYQGWKNSVRHNLSLNECFIKLPKGLGRPGKGH 120 121 YWTIDPASEFMFEEGSFRRRPRGFRRKCQALKPVYSMVNGLGFNHLPDTYGFQGSGGLSC 180 181 APNSLALEGGLGMMNGHLAGNVDGMALPSHSVPHLPSNGGHSYMGGCGGSAAGEYPHHDS 240 241 SVPASPLLPAGAGGVMEPHAVYSSSAAAWPPAASAALNSGASYIKQQPLSPCNPAANPLS 300 301 GSISTHSLEQPYLHQNSHNGPAELQGIPRYHSQSPSMCDRKEFVFSFNAMASSSMHTTGG 360 361 GSYYHQQVTYQDIKPCVM |
| Interface Residues: | 45, 88, 91, 93, 94, 95, 97, 98, 99, 101, 102, 111, 118, 142 |
| 3D-footprint Homologues: | 7yzb_A, 7yzg_A, 7yz7_A, 3l2c_A, 7vox_H, 2hdc_A, 6nce_A, 2uzk_A, 7vou_C, 2a07_J, 7yze_A, 7cby_C, 3co6_C, 6ako_C, 2c6y_A, 7tdw_A, 3g73_A, 6el8_A, 7tdx_A, 3qrf_G |
| Binding Motifs: | MA1606.1 awrTAAACAaa MA1606.2 rTAAACA |
| Binding Sites: | MA1606.2.10 / MA1606.2.13 / MA1606.2.14 / MA1606.2.16 / MA1606.2.17 / MA1606.2.2 / MA1606.2.3 / MA1606.2.4 / MA1606.2.5 / MA1606.2.7 MA1606.2.11 / MA1606.2.15 / MA1606.2.19 / MA1606.2.9 MA1606.1.1 MA1606.1.10 MA1606.1.11 MA1606.1.12 MA1606.1.13 MA1606.1.14 MA1606.1.14 / MA1606.1.15 MA1606.1.15 / MA1606.1.16 MA1606.1.17 MA1606.1.16 / MA1606.1.18 MA1606.1.17 / MA1606.1.19 MA1606.1.1 / MA1606.1.2 MA1606.1.18 / MA1606.1.20 MA1606.1.2 / MA1606.1.3 MA1606.1.3 / MA1606.1.4 MA1606.1.4 / MA1606.1.5 MA1606.1.5 / MA1606.1.6 MA1606.1.7 MA1606.1.8 MA1606.1.9 MA1606.1.12 MA1606.1.19 MA1606.1.20 MA1606.1.6 MA1606.2.1 / MA1606.2.18 MA1606.2.6 MA1606.2.20 MA1606.2.8 MA1606.2.12 |
| Publications: | Weirauch MT, Yang A, Albu M, Cote AG, Montenegro-Montero A, Drewe P, Najafabadi HS, Lambert SA, Mann I, Cook K, Zheng H, Goity A, van Bakel H, Lozano JC, Galli M, Lewsey MG, Huang E, Mukherjee T, Chen X, Reece-Hoyes JS, Govindarajan S, Shaulsky G, et al. Determination and inference of eukaryotic transcription factor sequence specificity. Cell. 2014 Sep 11;158(6):1431-43. doi: 10.1016/j.cell.2014.08.009. [Pubmed] |
| Related annotations: | PaperBLAST |
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