Transcription Factor

Accessions: CREM_HUMAN (HOCOMOCO 10)
Names: cAMP-responsive element modulator, CREM_HUMAN, ICER, Inducible cAMP early repressor
Organisms: Homo sapiens
Libraries: HOCOMOCO 10 1
1 Kulakovskiy IV, Vorontsov IE, Yevshin IS, Soboleva AV, Kasianov AS, Ashoor H, Ba-Alawi W, Bajic VB, Medvedeva YA, Kolpakov FA, Makeev VJ. HOCOMOCO: expansion and enhancement of the collection of transcription factor binding sites models. Nucleic Acids Res : (2016). [Pubmed]
Uniprot: Q03060
Length: 361
Pfam Domains: 118-156 pKID domain
300-356 bZIP transcription factor
305-353 Basic region leucine zipper
Sequence:
(in bold interface residues)
1 MSKCARKKYIKTNPRQMTMETVESQHDGSITASLTESKSAHVQTQTGQNSIPALAQVSVA 60
61 GSGTRRGSPAVTLVQLPSGQTIHVQGVIQTPQPWVIQSSEIHTVQVAAIAETDESAESEG 120
121 VIDSHKRREILSRRPSYRKILNELSSDVPGVPKIEEERSEEEGTPPSIATMAVPTSIYQT 180
181 STGQYIAIAQGGTIQISNPGSDGVQGLQALTMTNSGAPPPGATIVQYAAQSADGTQQFFV 240
241 PGSQVVVQDEETELAPSHMAAATGDMPTYQIRAPTAALPQGVVMAASPGSLHSPQQLAEE 300
301 ATRKRELRLMKNREAAKECRRRKKEYVKCLESRVAVLEVQNKKLIEELETLKDICSPKTD 360
361 Y
Interface Residues: 308, 311, 312, 313, 315, 316, 319, 320
3D-footprint Homologues: 1gd2_G, 7x5e_F, 4eot_A, 5t01_B, 1dh3_C, 5vpe_D
Binding Motifs: CREM_HUMAN.H10MO.C|M01067 srvTGACGTCA
Related annotations: PaperBLAST

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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.