Transcription Factor

Accessions: UP00465A (UniPROBE 20160601)
Names: Sin Three Binding protein, Stb4
Organisms: Saccharomyces cerevisiae
Libraries: UniPROBE 20160601 1
1 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed]
Description: Sin Three Binding protein : Putative transcription factor; contains a Zn(II)2Cys6 zinc finger domain characteristic of DNA-binding proteins; computational analysis suggests a role in regulation of expression of genes encoding transporters; binds Sin3p in a two-hybrid assay
Length: 39
Pfam Domains: 1-34 Fungal Zn(2)-Cys(6) binuclear cluster domain
Sequence:
(in bold interface residues)
1 KACELCKKRKVKCDGNNPCLNCSKHQKECRYDFKATNRK
Interface Residues: 7, 9, 10, 11, 12, 24, 25, 35
3D-footprint Homologues: 1f5e_P, 1hwt_C, 1pyi_A, 6o19_A, 2er8_C, 7uik_T, 3coq_A, 6gys_C, 1d66_B, 1zme_D
Binding Motifs: UP00465A_1 / UP00465A_2 mwbwwwttATCCGArvtyyyam
UP00465A_3 TCGGsCCGA
Binding Sites: ATATCCGA
CCTCGGAA
CTCGGAAA
CTCGGAAC
CTTCGGAA
GCTCGGAA
ACATCCGA
ATCCGAAA
ATCCGAAG
ATCCGAAT
ATCCGAGG
CATCCGAG
CTCGGAAG
CTCGGATA
CTCGGATC
CTTCCGAA
GATCCGAA
GTATCCGA
TATCCGAA
TCGGATAA
Publications: Gordân R, Murphy KF, McCord RP, Zhu C, Vedenko A, Bulyk ML. Curated collection of yeast transcription factor DNA binding specificity data reveals novel structural and gene regulatory insights. Genome Biol : (2011). [Pubmed]
Related annotations: PaperBLAST

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