Transcription Factor

						

			
Accessions: 2lef_A (3D-footprint 20231221)

			
Names: LEF-1, LEF1_MOUSE, LYMPHOID ENHANCER-BINDING FACTOR, Lymphoid enhancer-binding factor 1
Organisms: Mus musculus
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Uniprot: P27782
Length: 86
Pfam Domains:      3-71 HMG (high mobility group) box
     4-61 Domain of unknown function (DUF1898)
Sequence: 
(in bold interface residues)		   1 MHIKKPLNAFMLYMKEMRANVVAESTLKESAAINQILGRRWHALSREEQAKYYELARKER   60
  61 QLHMQLYPGWSARDNYGKKKKRKREK
Interface Residues: 5, 8, 10, 11, 14, 18, 29, 30, 31, 34, 72, 74, 76, 79, 81, 82, 83, 86
3D-footprint Homologues: 6jrp_D, 1qrv_A, 3u2b_C, 7m5w_A, 2gzk_A, 4s2q_D, 1j5n_A, 2lef_A, 4y60_C, 1o4x_B, 3f27_D, 1hry_A
Binding Motifs: 2lef_A CtTCAaAG
Binding Sites: 2lef_B
2lef_C
			
Publications: Love J. J., Li X., Case D. A., Giese K., Grosschedl R., Wright P. E. Structural basis for DNA bending by the architectural transcription factor LEF-1. Nature 376:791-795 (1995). [Pubmed]
Related annotations: PaperBLAST

	
			


			

				

				
				
				
				

			

			

		

	
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