Transcription Factor
| Accessions: | 5lty_K (3D-footprint 20231221) |
| Names: | Caudal-type homeobox protein 2, CDX-3, CDX2_HUMAN, Homeobox protein CDX-2 |
| Organisms: | Homo sapiens |
| Libraries: | 3D-footprint 20231221 1 1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed] |
| Uniprot: | Q99626 |
| Length: | 71 |
| Pfam Domains: | 4-59 Homeobox domain |
| Sequence: (in bold interface residues) | 1 TKDKYRVVYTDHQRLELEKEFHYSRYITIRRKAELAATLGLSERQVKIWFQNRRAKERKI 60 61 NKKKLQQQQQQ |
| Interface Residues: | 3, 4, 5, 6, 44, 45, 47, 48, 51, 52, 55, 56, 57, 58, 59 |
| 3D-footprint Homologues: | 3d1n_M, 3lnq_A, 1nk2_P, 1jgg_B, 7q3o_C, 6es3_K, 2ld5_A, 3a01_E, 2h1k_B, 7psx_B, 2lkx_A, 6a8r_A, 3cmy_A, 2hdd_A, 1fjl_B, 5jlw_D, 3rkq_B, 2r5y_A, 1b72_A, 4xrs_G, 2hos_A, 1ig7_A, 5zfz_A, 4cyc_A, 2d5v_B, 5flv_I, 1puf_A, 5zjt_E, 1e3o_C, 1au7_A, 1le8_A, 7xrc_C, 2xsd_C, 4qtr_D, 1mnm_C, 5hod_A, 1puf_B, 1k61_B, 4xrm_B, 1zq3_P, 1o4x_A, 1le8_B, 1du0_A, 3l1p_A, 8g87_X, 6m3d_C |
| Binding Motifs: | 5lty_K tnnTAAa |
| Binding Sites: | 5lty_A 5lty_F |
| Publications: | Yin Y, Morgunova E, Jolma A, Kaasinen E, Sahu B, Khund-Sayeed S, Das PK, Kivioja T, Dave K, Zhong F, Nitta KR, Taipale M, Popov A, Ginno PA, Domcke S, Yan J, Schübeler D, Vinson C, Taipale J. Impact of cytosine methylation on DNA binding specificities of human transcription factors. Science : (2017). [Pubmed] |
| Related annotations: | PaperBLAST |
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