Transcription Factor

Accessions: 2z33_A (3D-footprint 20231221)
Names: PHOB_ECOLI, Phosphate regulon transcriptional regulatory protein phoB
Organisms: Escherichia coli, strain K12
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Uniprot: P0AFJ5
Length: 104
Pfam Domains: 26-100 Transcriptional regulatory protein, C terminal
Sequence:
(in bold interface residues)
1 MAVEEVIEMQGLSLDPTSHRVMAGEEPLEMGPTEFKLLHFFMTHPERVYSREQLLNHVWG 60
61 TNVYVEDRTVDVHIRRLRKALEPGGHDRMVQTVRGTGYRFSTRF
Interface Residues: 67, 68, 69, 71, 72, 73, 75, 76, 94
3D-footprint Homologues: 8jo2_H, 8hml_B, 4kfc_B, 6lxn_A, 4nhj_A, 7e1b_B, 5ed4_A, 8hih_Q, 2z33_A, 5x5l_H
Binding Motifs: 2z33_A TGTcnnA
Binding Sites: 2z33_B
2z33_C
Publications: Yamane T, Okamura H, Ikeguchi M, Nishimura Y, Kidera A. Water-mediated interactions between DNA and PhoB DNA-binding/transactivation domain: NMR-restrained molecular dynamics in explicit water environment. Proteins 71:1970-83 (2008). [Pubmed]
Related annotations: PaperBLAST

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