Transcription Factor
| Accessions: | UP00509A (UniPROBE 20160601) |
| Names: | CG3871, D-six4, Dmel\CG3871, Dsix4, Six4, six4/5 |
| Organisms: | Drosophila melanogaster |
| Libraries: | UniPROBE 20160601 1 1 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed] |
| Description: | Six4 |
| Length: | 74 |
| Pfam Domains: | 15-65 Homeobox domain 24-63 Homeodomain leucine-zipper encoding, Homez 29-63 Homeobox KN domain |
| Sequence: (in bold interface residues) | 1 PLPKTIWDGEETVYCFKEKSRNALKDCYLTNRYPTPDEKKTLAKKTGLTLTQVSNWFKNR 60 61 RQRDRTPQQRPDIM |
| Interface Residues: | 4, 51, 52, 54, 55, 58, 59, 62, 63, 65, 66 |
| 3D-footprint Homologues: | 4xrs_G, 2ld5_A, 5jlw_D, 1ig7_A, 2xsd_C, 7q3o_C, 1e3o_C, 7xrc_C, 1au7_A, 1le8_A, 1b72_A, 3d1n_M, 1o4x_A, 7psx_B, 5zfz_A, 4cyc_A, 2d5v_B, 1le8_B, 6fqp_B, 1du0_A, 5flv_I, 3l1p_A, 1puf_A, 1jgg_B, 5zjt_E, 4qtr_D, 3a01_E, 2h1k_B, 1mnm_C, 6fqq_E, 5hod_A, 3lnq_A, 2lkx_A, 1puf_B, 1k61_B, 6a8r_A, 4xrm_B, 3cmy_A, 2hdd_A, 1nk2_P, 1fjl_B, 3rkq_B, 2r5y_A, 1zq3_P, 8g87_X, 6es3_K, 2hos_A, 6m3d_C |
| Binding Motifs: | UP00509A_1 ywmarrywTGACACCymbhwrw |
| Binding Sites: | AAGATATC AATGATAC AGATATCA AGGTATCA AGGTGTCA AGTATCAT ATGACACC ATGATACC ATGATCCC CGGTGTCA CTGACACC GGGTATCA GGGTGTCA GGTATCAA GGTATCAC GGTGTCAA GGTGTCAC GTATCATA TGACACCA GACACCCC |
| Publications: | Busser BW, Shokri L, Jaeger SA, Gisselbrecht SS, Singhania A, Berger MF, Zhou B, Bulyk ML, Michelson AM. Molecular mechanism underlying the regulatory specificity of a Drosophila homeodomain protein that specifies myoblast identity. Development 139:1164-74 (2012). [Pubmed] |
| Related annotations: | PaperBLAST |
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