Transcription Factor

Accessions: IKZF1_MOUSE (HOCOMOCO 10)
Names: DNA-binding protein Ikaros, Ikaros family zinc finger protein 1, IKZF1_MOUSE, Lymphoid transcription factor LyF-1
Organisms: Mus musculus
Libraries: HOCOMOCO 10 1
1 Kulakovskiy IV, Vorontsov IE, Yevshin IS, Soboleva AV, Kasianov AS, Ashoor H, Ba-Alawi W, Bajic VB, Medvedeva YA, Kolpakov FA, Makeev VJ. HOCOMOCO: expansion and enhancement of the collection of transcription factor binding sites models. Nucleic Acids Res : (2016). [Pubmed]
Length: 517
Pfam Domains: 132-154 Zinc-finger double domain
144-166 C2H2-type zinc finger
144-166 Zinc finger, C2H2 type
158-181 Zinc-finger double domain
172-194 C2H2-type zinc finger
172-194 Zinc finger, C2H2 type
187-210 Zinc-finger double domain
200-223 C2H2-type zinc finger
200-223 Zinc finger, C2H2 type
Sequence:
(in bold interface residues)
1 MDVDEGQDMSQVSGKESPPVSDTPDEGDEPMPVPEDLSTTSGAQQNSKSDRGMGSNVKVE 60
61 TQSDEENGRACEMNGEECAEDLRMLDASGEKMNGSHRDQGSSALSGVGGIRLPNGKLKCD 120
121 ICGIVCIGPNVLMVHKRSHTERPFQCNQCGASFTQKGNLLRHIKLHSGEKPFKCHLCNYA 180
181 CRRRDALTGHLRTHSVGKPHKCGYCGRSYKQRSSLEEHKERCHNYLESMGLPGVCPVIKE 240
241 ETNHNEMAEDLCKIGAERSLVLDRLASNVAKRKSSMPQKFLGDKCLSDMPYDSANYEKED 300
301 MMTSHVMDQAINNAINYLGAESLRPLVQTPPGSSEVVPVISSMYQLHKPPSDGPPRSNHS 360
361 AQDAVDNLLLLSKAKSVSSEREASPSNSCQDSTDTESNAEEQRSGLIYLTNHINPHARNG 420
421 LALKEEQRAYEVLRAASENSQDAFRVVSTSGEQLKVYKCEHCRVLFLDHVMYTIHMGCHG 480
481 CHGFRDPFECNMCGYHSQDRYEFSSHITRGEHRYHLS
Interface Residues: 127, 128, 129, 130, 131, 133, 134, 136, 137, 140, 141, 144, 154, 155, 156, 157, 158, 160, 161, 162, 165, 182, 183, 184, 185, 186, 187, 188, 189, 190, 210, 211, 212, 213, 214, 215, 216, 217, 221, 242, 243
3D-footprint Homologues: 8cuc_F, 7y3l_A, 7n5w_A, 8ssq_A, 7w1m_H, 5k5l_F, 8ssu_A, 5v3j_F, 2i13_A, 5kkq_D, 5yel_A, 5ei9_F, 7eyi_G, 8h9h_G, 7y3m_I, 6e94_A, 2jpa_A, 6ml4_A, 6blw_A, 7ysf_A, 6wmi_A, 1yuj_A, 2kmk_A, 6jnm_A, 1tf3_A, 3uk3_C, 5k5i_A, 1tf6_A, 5und_A, 2gli_A, 1ubd_C, 4x9j_A, 1mey_C, 1f2i_J, 6u9q_A, 7txc_E, 5kl3_A, 2drp_D, 1g2f_F, 5yj3_D, 4m9v_C, 2lt7_A, 6a57_A, 1llm_D, 8gn3_A, 2wbs_A
Binding Motifs: IKZF1_MOUSE.H10MO.C|M01169 yTGGGArr
Related annotations: PaperBLAST

Disclaimer and license

These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.