Transcription Factor

Accessions: 1an4_A (3D-footprint 20231221), 1an4_B (3D-footprint 20231221)
Names: bHLHb11, Class B basic helix-loop-helix protein 11, Major late transcription factor 1, UPSTREAM STIMULATORY FACTOR, Upstream stimulatory factor 1, USF1_HUMAN
Organisms: Homo sapiens
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Uniprot: P22415
Length: 65
Pfam Domains: 5-59 Helix-loop-helix DNA-binding domain
Sequence:
(in bold interface residues)
1 MDEKRRAQHNEVERRRRDKINNWIVQLSKIIPDSSMESTKSGQSKGGILSKASDYIQELR 60
61 QSNHR
Interface Residues: 6, 8, 9, 10, 12, 13, 16, 17, 43, 45
3D-footprint Homologues: 1a0a_B, 1an4_A, 6g1l_A, 4h10_A, 7ssa_L, 5i50_B, 7d8t_A, 4zpk_A, 7xi3_A, 5nj8_D, 1am9_A, 7f2f_B, 5eyo_A, 5v0l_A, 7rcu_E, 5gnj_I, 8osl_P
Binding Motifs: 1an4_AB AnncCACGTGAnC
1an4_A gTGAnc
Binding Sites: 1an4_C
1an4_D
Publications: Ferre-D'Amare A. R., Pognonec P., Roeder R. G., Burley S. K. Structure and function of the b/HLH/Z domain of USF. EMBO J. 13:180-189 (1994). [Pubmed]
Related annotations: PaperBLAST

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