Transcription Factor
| Accessions: | 4l0y_A (3D-footprint 20231221) |
| Names: | Acute myeloid leukemia 1 protein, CBF-alpha-2, Core-binding factor subunit alpha-2, Oncogene AML-1, PEA2-alpha B, PEBP2-alpha B, Polyomavirus enhancer-binding protein 2 alpha B subunit, Runt-related transcription factor 1, RUNX1_MOUSE, SL3-3 enhancer factor 1 alpha B subunit, SL3/AKV core-binding factor alpha B subunit |
| Organisms: | Mus musculus |
| Libraries: | 3D-footprint 20231221 1 1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed] |
| Uniprot: | Q03347 |
| Length: | 128 |
| Pfam Domains: | 2-128 Runt domain |
| Sequence: (in bold interface residues) | 1 SMVEVLADHPGELVRTDSPNFLCSVLPTHWRCNKTLPIAFKVVALGDVPDGTLVTVMAGN 60 61 DENYSAELRNATAAMKNQVARFNDLRFVGRSGRGKSFTLTITVFTNPPQVATYHRAIKIT 120 121 VDGPREPR |
| Interface Residues: | 31, 93, 121, 122, 125, 128 |
| 3D-footprint Homologues: | 6vg8_D, 3wts_A, 6vgd_D, 4l0y_A, 4l18_E |
| Binding Motifs: | 4l0y_A AAGCCACA 4l0y_AB AAGCCACATCCT |
| Binding Sites: | 4l0y_C 4l0y_D |
| Publications: | Shrivastava T, Mino K, Babayeva N.D, Baranovskaya O.I, Rizzino A, Tahirov T.H. Structural basis of Ets1 activation by Runx1. Leukemia 28:2040-8 (2014). [Pubmed] |
| Related annotations: | PaperBLAST |
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