Transcription Factor
| Accessions: | CEBPB_DBD (HumanTF 1.0), CEBPB_TF2 (HumanTF2 1.0) |
| Names: | CEBPB, CEBPB protein, Fragment, Q9BSC0_HUMAN |
| Organisms: | Homo sapiens |
| Libraries: | HumanTF 1.0 1, HumanTF2 1.0 2 1 Jolma A, Yan J, Whitington T, Toivonen J, Nitta KR, Rastas P, Morgunova E, Enge M, Taipale M, Wei G, Palin K, Vaquerizas JM, Vincentelli R, Luscombe NM, Hughes TR, Lemaire P, Ukkonen E, Kivioja T, Taipale J. DNA-Binding Specificities of Human Transcription Factors. Cell. 2013 Jan 17;152(1-2):327-39. [Pubmed] 2 Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed] |
| Uniprot: | Q9BSC0 |
| Notes: | Ensembl ID: ENSG00000172216; DNA-binding domain sequence; TF family: bZIP; Clone source: MGC, Ensembl ID: ENSG00000172216; Construct type: TF2(3xFLAG); TF family: bZIP; Clone source: Jolma et al. 2013 |
| Length: | 94 |
| Pfam Domains: | 19-72 Basic region leucine zipper 20-78 bZIP transcription factor |
| Sequence: (in bold interface residues) | 1 MAPAPSQVKSKAKKTVDKHSDEYKIRRERNNIAVRKSRDKAKMRNLETQHKVLELTAENE 60 61 RLQKKVEQLSRELSTLRNLFKQLPEPLLASSGHC |
| Interface Residues: | 27, 30, 31, 33, 34, 37, 38 |
| 3D-footprint Homologues: | 6mg1_B, 1nwq_C, 2c9l_Z, 2dgc_A |
| Binding Motifs: | CEBPB_DBD rTTrCGCAAy ATF4_CEBPB ggrTGAyGCAAym FLI1_CEBPB rvCGGAwrTTGCGCAAy GCM1_CEBPB_1 ATGcGGGyrkrTTGCGYAAy GCM1_CEBPB_2 rTGcGGGyrgrkrTTGCGYAAy GCM1_CEBPB_2_3 rTRcGGGyrgkrTTGCGYAAy TEAD4_CEBPB rTTGCGyAAyvsckhGGaATGy |
| Publications: | Jolma A, Yan J, Whitington T, Toivonen J, Nitta KR, Rastas P, Morgunova E, Enge M, Taipale M, Wei G, Palin K, Vaquerizas JM, Vincentelli R, Luscombe NM, Hughes TR, Lemaire P, Ukkonen E, Kivioja T, Taipale J. DNA-Binding Specificities of Human Transcription Factors. Cell. 2013 Jan 17;152(1-2):327-39. [Pubmed] Jolma A, Yin Y, Nitta KR, Dave K, Popov A, Taipale M, Enge M, Kivioja T, Morgunova E, Taipale J. DNA-dependent formation of transcription factor pairs alters their binding specificity. Nature 527:384-8 (2015). [Pubmed] |
| Related annotations: | PaperBLAST |
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