Transcription Factor

						

			
Accessions: 1exi_A (3D-footprint 20231221), 1exj_A (3D-footprint 20231221)

			
Names: BMRR_BACSU, MULTIDRUG-EFFLUX TRANSPORTER REGULATOR
Organisms: Bacillus subtilis, strain 168
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Uniprot: P39075
Length: 275
Pfam Domains:      4-71 MerR HTH family regulatory protein
     5-43 MerR family regulatory protein
  122-274 GyrI-like small molecule binding domain
Sequence: 
(in bold interface residues)		   1 ESYYSIGEVSKLANVSIKALRYYDKIDLFKPAYVDPDTSYRYYTDSQLIHLDLIKSLKYI   60
  61 GTPLEEMKKAQDLEMEELFAFYTEQERQIREKLDFLSALEQTISLVKKRMKRQMEYPALG  120
 121 EVFVLDEEEIRIIQTEAEGIGPENVLNASYSKLKKFIESADGFTNNSYGATFSFQPYTSI  180
 181 DEMTYRHIFTPVLTNKQISSITPDMEITTIPKGRYACIAYNFSPEHYFLNLQKLIKYIAD  240
 241 RQLTVVSDVYELIIPIHYSPKKQEEYRVEMKIRIA
Interface Residues: 18, 21, 22, 25, 38, 40, 41
3D-footprint Homologues: 6xh7_H, 1r8e_A, 5d8c_A, 6xl5_H, 2vz4_A, 6jgx_B, 7ckq_G, 2zhg_A, 6ldi_G, 1r8d_B, 7tea_B, 4r24_B
Binding Motifs: 1exi_A CCCT
1exj_A cCcT
Binding Sites: 1exi_M / 1exj_M
			
Publications: Heldwein E.E, Brennan R.G. Crystal structure of the transcription activator BmrR bound to DNA and a drug. Nature 409:378-82 (2001). [Pubmed]
Related annotations: PaperBLAST

	
			


			

				

				
				
				
				

			

			

		

	
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