Transcription Factor

Accessions: 5d8c_B (3D-footprint 20231221)
Names: MerR family regulator protein, Y186_HAEIN
Organisms: Haemophilus influenzae, strain ATCC 51907 / DSM 11121 / KW20 / Rd
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Uniprot: P44558
Length: 128
Pfam Domains: 5-70 MerR HTH family regulatory protein
6-43 MerR family regulatory protein
49-109 MerR, DNA binding
Sequence:
(in bold interface residues)
1 NAMTYTTAKAAEKIGISAYTLRFYDKEGLLPNVGRDEYGNRRFTDKDLQWLSLLQCLKNT 60
61 GMSLKDIKRFAECTIIGDDTIEERLSLFENQTKNVKCQIAELKRYLDLLEYKLAFYQKAK 120
121 ALGSVKAV
Interface Residues: 19, 22, 23, 26, 27, 40, 41
3D-footprint Homologues: 5i44_I, 1r8d_B, 6xl5_H, 4r4e_B, 1r8e_A, 7ckq_G, 5c8e_C, 6ldi_G, 2vz4_A, 7tea_B, 5d8c_A, 6xh7_H, 2zhg_A, 7tec_A, 6jgx_B
Binding Motifs: 5d8c_AB AGAGnnnnCTCT
Binding Sites: 5d8c_C
5d8c_D
Publications: Couñago RM, Chen NH, Chang CW, Djoko KY, McEwan AG, Kobe B. Structural basis of thiol-based regulation of formaldehyde detoxification in H. influenzae by a MerR regulator with no sensor region 44:6981-93 (Nucleic). [Pubmed]
Related annotations: PaperBLAST

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