Transcription Factor

Accessions: T044419_1.02 (CISBP 1.02)
Names: T044419_1.02;, ZIC3
Organisms: Homo sapiens
Libraries: CISBP 1.02 1
1 Weirauch MT, Yang A, Albu M, Cote AG, Montenegro-Montero A, Drewe P, Najafabadi HS, Lambert SA, Mann I, Cook K, Zheng H, Goity A, van Bakel H, Lozano JC, Galli M, Lewsey MG, Huang E, Mukherjee T, Chen X, Reece-Hoyes JS, Govindarajan S, Shaulsky G, et al. Determination and inference of eukaryotic transcription factor sequence specificity. Cell. 2014 Sep 11;158(6):1431-43. doi: 10.1016/j.cell.2014.08.009. [Pubmed]
Notes: family:C2H2 ZF
Length: 457
Pfam Domains: 297-322 Zinc finger, C2H2 type
301-322 C2H2-type zinc finger
315-340 Zinc-finger double domain
328-352 C2H2-type zinc finger
328-352 Zinc finger, C2H2 type
344-371 Zinc-finger double domain
358-382 C2H2-type zinc finger
376-399 Zinc-finger double domain
388-408 Zinc finger, C2H2 type
388-408 C2H2-type zinc finger
Sequence:
(in bold interface residues)
1 MTMLLDGGPQFPGLGVGSFGAPRHHEMPNREPAGMGLNPFGDSTHAAAAAAAAAAFKLSP 60
61 AAAHDLSSGQSSAFTPQGSGYANALGHHHHHHHHHHHTSQVPSYGGAASAAFNSTREFLF 120
121 RQRSSGLSEAASGGGQHGLFAGSASSLHAPAGIPEPPSYLLFPGLHEQGAGHPSPTGHVD 180
181 NNQVHLGLRGELFGRADPYRPVASPRTDPYAAGAQFPNYSPMNMNMGVNVAAHHGPGAFF 240
241 RYMRQPIKQELSCKWIDEAQLSRPKKSCDRTFSTMHELVTHVTMEHVGGPEQNNHVCYWE 300
301 ECPREGKSFKAKYKLVNHIRVHTGEKPFPCPFPGCGKIFARSENLKIHKRTHTGEKPFKC 360
361 EFEGCDRRFANSSDRKKHMHVHTSDKPYICKVCDKSYTHPSSLRKHMKCCPAWYPGQSLI 420
421 PDEELDTDVGMQQPALHNTTYPKCRVNAEPTVQEMIY
Interface Residues: 242, 243, 244, 274, 276, 277, 280, 310, 311, 312, 313, 314, 316, 317, 321, 328, 340, 341, 342, 343, 344, 346, 347, 348, 349, 350, 352, 353, 356, 365, 370, 371, 372, 373, 374, 375, 376, 377, 378, 381, 398, 399, 400, 401, 402, 404, 405
3D-footprint Homologues: 5v3j_F, 6wmi_A, 5yel_A, 1ubd_C, 7w1m_H, 8cuc_F, 7n5w_A, 1tf3_A, 2gli_A, 1g2f_F, 8ssq_A, 1tf6_A, 6ml4_A, 5kkq_D, 8ssu_A, 4x9j_A, 5kl3_A, 5ei9_F, 7eyi_G, 8h9h_G, 7ysf_A, 5k5i_A, 2lt7_A, 2i13_A, 8gn3_A, 6e94_A, 2kmk_A, 6jnm_A, 3uk3_C, 7y3l_A, 5und_A, 1llm_D, 6blw_A, 2v6e_B, 1mey_C, 6u9q_A, 7txc_E, 4m9v_C, 7y3m_I, 6a57_A, 2jpa_A, 6sjf_B, 2wbs_A, 1f2i_J, 5yj3_D, 2drp_D
Binding Motifs: M4149_1.02 yGGGkggtc
Related annotations: PaperBLAST

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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.