Transcription Factor

Accessions: 1pue_E (3D-footprint 20231221)
Names: 31 kDa-transforming protein, SFFV proviral integration 1 protein, SPI1_MOUSE, TRANSCRIPTION FACTOR PU.1 (TF PU.1)
Organisms: Mus musculus
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Uniprot: P17433
Length: 88
Pfam Domains: 1-85 Ets-domain
Sequence:
(in bold interface residues)
1 KIRLYQFLLDLLRSGDMKDSIWWVDKDKGTFQFSSKHKEALAHRWGIQKGNRKKMTYEKM 60
61 ARALRNYGKTGEVKKVKKKLTYQFSGEV
Interface Residues: 37, 58, 59, 61, 62, 63, 65, 66, 79
3D-footprint Homologues: 1if1_B, 7jsa_J, 3zp5_A, 8ee9_F, 4mhg_A, 2stt_A, 1dux_F, 4uno_A, 3jtg_A, 4l18_B, 1awc_A, 4lg0_B, 1yo5_C, 4bqa_A, 1bc8_C, 4iri_A
Binding Motifs: 1pue_E GGGRm
Binding Sites: 1pue_A
1pue_B
Publications: Kodandapani R., Pio F., Ni C.-Z., Piccialli G., Klemsz M., McKercher S., Maki R. A., Ely K. R. A new pattern for helix-turn-helix recognition revealed by the PU.1 ETS-domain-DNA complex. Nature 380:456-460 (1996). [Pubmed]
Related annotations: PaperBLAST

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