Transcription Factor
| Accessions: | UP00299A (UniPROBE 20160601) |
| Names: | LPI16C, Protein TBF1, TBF alpha, Tbf1, TTAGGG repeat-binding factor 1, YPL128C |
| Organisms: | Saccharomyces cerevisiae |
| Libraries: | UniPROBE 20160601 1 1 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed] |
| Uniprot: | Q02457 |
| Description: | Telobox-containing general regulatory factor; binds to TTAGGG repeats within subtelomeric anti-silencing regions (STARs) and possibly throughout the genome and mediates their insulating capacity by... |
| Length: | 148 |
| Pfam Domains: | 52-106 Myb-like DNA-binding domain 54-107 Myb-like DNA-binding domain |
| Sequence: (in bold interface residues) | 1 SSKNPAITQSIVDAAVAASMSNSSSGPHSSHNNSSNSNNNGSIGLRKPKAKRTWSKEEEE 60 61 ALVEGLKEVGPSWSKILDLYGPGGKITENLKNRTQVQLKDKARNWKLQYLKSGKPLPDYL 120 121 IKVTGNLEKIYKAKKKFSQSPNSSTIME |
| Interface Residues: | 51, 87, 88, 91, 92, 93, 94, 95, 96, 99, 100, 103, 106 |
| 3D-footprint Homologues: | 1w0t_A, 7c4r_A, 1vfc_A, 3zqc_A, 3osg_A, 2kdz_A, 2qhb_A |
| Binding Motifs: | UP00299A_1 yyysgwARCCCTAAyacgsm |
| Binding Sites: | AAACCCTA AACCCTAA AACCCTAC AACCCTAG AACCCTAT AAGCCCTA ACCCTAAT AGCCCTAA AGCCCTAG CAACCCTA CAGCCCTA GAACCCTA GAGCCCTA TAACCCTA TACCCTAA TAGCCCTA AACCCTGA AGCCCTAT AGGGTTGG TGCCCTAA |
| Publications: | *Zhu C, *Byers K, *McCord RP, Shi Z, Berger MF, Newburger D, Saulrieta K, Smith Z, Shah M, Radhakrishnan M, Philippakis AA, Hu Y, De Masi F, Pacek M, Rolfs A , Murthy TVS, LaBaer J, Bulyk ML. High-Resolution DNA Binding Specificity Analysis of Yeast Transcription Factors. Genome Research. Epub January 21, 2009, doi:10.1101/gr.090233.108 (*co-1st authors). [Pubmed] |
| Related annotations: | PaperBLAST |
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