Transcription Factor
| Accessions: | 4zpr_A (3D-footprint 20231221) |
| Names: | ARNT protein, ARNT_MOUSE, Aryl hydrocarbon receptor nuclear translocator, Dioxin receptor, nuclear translocator, HIF-1-beta, HIF1-beta, Hypoxia-inducible factor 1-beta |
| Organisms: | Mus musculus |
| Libraries: | 3D-footprint 20231221 1 1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed] |
| Uniprot: | P53762 |
| Length: | 235 |
| Pfam Domains: | 5-54 Helix-loop-helix DNA-binding domain 61-119 PAS fold 149-212 PAS fold 155-212 PAS fold |
| Sequence: (in bold interface residues) | 1 ERLARENHSEIERRRRNKMTAYITELSDMVPTALARKPDKLTILRMAVSHMKSLTDQELK 60 61 HLILEAADGFLFIVSGRVVYVSDSVTPVLNQPQSEWFGSTLYDQVHPDDVDKLREQLSRR 120 121 SFICRMRCVHCTGYVAIGRLQTEFISRHNIEGIFTFVDHRCVATVGYQPQELLGKNIVEF 180 181 CHPEDQQLLRDSFQQVVKLKGQVLSVMFWMRTSSFTFQNPYSDEIEYIICTNTNV |
| Interface Residues: | 5, 7, 8, 9, 11, 12, 15, 16, 40, 91, 93, 94, 97, 102 |
| 3D-footprint Homologues: | 1a0a_B, 1an4_A, 4zpk_B, 7d8t_A, 5i50_B, 4h10_A, 7xi3_A, 5v0l_A, 4zpr_B, 1am9_A, 7rcu_E, 4h10_B, 5eyo_A, 7ssa_L, 5nj8_D, 4zpk_A, 8osl_O, 6g1l_A, 5gnj_I, 5sy7_B, 8osl_P, 5nj8_C, 7xhv_B, 7xi3_B, 5v0l_B, 3oqg_A |
| Binding Motifs: | 4zpr_AB gCACGt |
| Publications: | Wu D, Potluri N, Lu J, Kim Y, Rastinejad F. Structural integration in hypoxia-inducible factors. Nature 524:303-8 (2015). [Pubmed] |
| Related annotations: | PaperBLAST |
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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.