Transcription Factor

Accessions: 6oen_N (3D-footprint 20231221)
Names: High mobility group protein 1, High mobility group protein B1, HMG-1, HMGB1_HUMAN
Organisms: Homo sapiens
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Uniprot: P09429
Length: 36
Pfam Domains: 1-35 HMG (high mobility group) box
Sequence:
(in bold interface residues)
1 PSAFFLFCSEYRPKIKGEHPGIGDVAKKLGEMWNNT
Interface Residues: 2, 4, 5, 8, 12, 22, 23, 24, 26
3D-footprint Homologues: 7m5w_A, 1hry_A, 3u2b_C, 1j5n_A, 4s2q_D, 6jrp_D, 2gzk_A, 1qrv_A
Binding Motifs: 6oen_ADN GTnnnnnnnnnnnctnnnnnTG
Binding Sites: 6oen_G
6oen_J
Publications: Chen X, Cui Y, Best RB, Wang H, Zhou ZH, Yang W, Gellert M. Cutting antiparallel DNA strands in a single active site. Nat Struct Mol Biol 27:119-126 (2020). [Pubmed]
Related annotations: PaperBLAST

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