Transcription Factor

						

			
Accessions: 2wt7_A (3D-footprint 20231221)

			
Names: Cellular oncogene fos, FOS_MOUSE, Proto-oncogene c-Fos, PROTO-ONCOGENE PROTEIN C-FOS
Organisms: Mus musculus
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Uniprot: P01101
Length: 63
Pfam Domains:      1-52 Basic region leucine zipper
     2-57 bZIP transcription factor
     2-57 bZIP Maf transcription factor
Sequence: 
(in bold interface residues)		   1 EKRRIRRERNKMAAAKCRNRRRELTDTLQAETDQLEDEKSALQTEIANLLKEKEKLEFIL   60
  61 AAH
Interface Residues: 6, 7, 10, 11, 13, 14, 17, 18, 21
3D-footprint Homologues: 7x5e_F, 1skn_P, 2wt7_A, 7x5e_E, 6mg1_B, 1nwq_C, 5vpe_D, 4eot_A, 5vpe_C
Binding Motifs: 2wt7_A sTCAt
2wt7_AB TGAGTnaGCa
Binding Sites: 2wt7_C
2wt7_D
			
Publications: Pogenberg V, Consani Textor L, Vanhille L, Holton S.J, Sieweke M.H, Wilmanns M. Design of a bZip transcription factor with homo/heterodimer-induced DNA-binding preference. Structure (London, England : 1993) 22:466-77 (2014). [Pubmed]
Related annotations: PaperBLAST

	
			


			

				

				
				
				
				

			

			

		

	
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