Transcription Factor

Accessions: UP00075A (UniPROBE 20160601)
Names: Sox-15, SOX-15 protein, Sox15, SRY-box containing gene 15
Organisms: Mus musculus
Libraries: UniPROBE 20160601 1
1 Hume MA, Barrera LA, Gisselbrecht SS, Bulyk ML. UniPROBE, update 2015: new tools and content for the online database of protein-binding microarray data on protein-DNA interactions. Nucleic Acids Res : (2015). [Pubmed]
Uniprot: P43267
Description: SRY-box containing gene 15
Length: 101
Pfam Domains: 16-78 Domain of unknown function (DUF1898)
17-85 HMG (high mobility group) box
Sequence:
(in bold interface residues)
1 EAGGSPGASGGLPLEKVKRPMNAFMVWSSVQRRQMAQQNPKMHNSEISKRLGAQWKLLGD 60
61 EEKRPFVEEAKRLRARHLRDYPDYKYRPRRKSKNSSTGSVP
Interface Residues: 19, 22, 24, 25, 26, 28, 32, 43, 44, 45, 48, 86, 90
3D-footprint Homologues: 4s2q_D, 1qrv_A, 3tmm_A, 4y60_C, 2gzk_A, 1j5n_A, 6jrp_D, 2lef_A, 3u2b_C, 1o4x_B, 7m5w_A, 3f27_D, 1hry_A, 3tq6_B, 1ckt_A
Binding Motifs: UP00075A_1 wrkwgAACAATwrrtwt
UP00075A_2 btramTGwmATtysr
Binding Sites: ATTATAAT
AAACAAAG
AACAAAAG
AACAAAGG
AACAATAA
AACAATAG
AACAATTA
AAGACAAT
AATTCAAT
AATTGTTC
ACAATAGA
ACAATTAA
AGAACAAT
AGACAATA
ATTGTTAA
ATTGTTTC
CATTAATA
CATTGTTA
GAACAATA
TAACAATA
Publications: Badis G, Berger M.F, Philippakis A.A, Talukder S, Gehrke A.R, Jaeger S.A, Chan E.T, Metzler G, Vedenko A, Chen X, Kuznetsov H, Wang C.F, Coburn D, Newburger D.E, Morris Q, Hughes T.R, Bulyk M.L. Diversity and complexity in DNA recognition by transcription factors. Science (New York, N.Y.) 324:1720-3 (2009). [Pubmed]
Related annotations: PaperBLAST

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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.