Transcription Factor
| Accessions: | ETV2_DBD (HumanTF 1.0) |
| Names: | ETS translocation variant 2, ETV2, ETV2 protein, Q3KNT2_HUMAN |
| Organisms: | Homo sapiens |
| Libraries: | HumanTF 1.0 1 1 Jolma A, Yan J, Whitington T, Toivonen J, Nitta KR, Rastas P, Morgunova E, Enge M, Taipale M, Wei G, Palin K, Vaquerizas JM, Vincentelli R, Luscombe NM, Hughes TR, Lemaire P, Ukkonen E, Kivioja T, Taipale J. DNA-Binding Specificities of Human Transcription Factors. Cell. 2013 Jan 17;152(1-2):327-39. [Pubmed] |
| Uniprot: | Q3KNT2 |
| Notes: | Ensembl ID: ENSG00000105672; DNA-binding domain sequence; TF family: ETS; Clone source: Megaman |
| Length: | 126 |
| Pfam Domains: | 25-105 Ets-domain |
| Sequence: (in bold interface residues) | 1 MAEPSPQSDRASLARCPKTNHRGPIQLWQFLLELLHDGARSSCIRWTGNSREFQLCDPKE 60 61 VARLWGERKRKPGMNYEKLSRGLRYYYRRDIVRKSGGRKYTYRFGGRVPSLAYPDCAGGG 120 121 RGAETQ |
| Interface Residues: | 77, 78, 81, 82, 84, 85, 99 |
| 3D-footprint Homologues: | 8smh_F, 8smj_F, 7jsa_J, 8ee9_F, 1yo5_C |
| Binding Motifs: | ETV2_DBD aACCGGAARYr |
| Publications: | Jolma A, Yan J, Whitington T, Toivonen J, Nitta KR, Rastas P, Morgunova E, Enge M, Taipale M, Wei G, Palin K, Vaquerizas JM, Vincentelli R, Luscombe NM, Hughes TR, Lemaire P, Ukkonen E, Kivioja T, Taipale J. DNA-Binding Specificities of Human Transcription Factors. Cell. 2013 Jan 17;152(1-2):327-39. [Pubmed] |
| Related annotations: | PaperBLAST |
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