Transcription Factor

						

			
Accessions: OSR1 (HT-SELEX2 May2017)

			
Names: ENSG00000143867, OSR1
Organisms: Homo sapiens
Libraries: HT-SELEX2 May2017 1
1 Yin Y, Morgunova E, Jolma A, Kaasinen E, Sahu B, Khund-Sayeed S, Das PK, Kivioja T, Dave K, Zhong F, Nitta KR, Taipale M, Popov A, Ginno PA, Domcke S, Yan J, Schübeler D, Vinson C, Taipale J. Impact of cytosine methylation on DNA binding specificities of human transcription factors. Science : (2017). [Pubmed]
Notes: TF family: Znf_C2H2 experiment: HT-SELEX Hamming distance: 1 cycle: 3, TF family: Znf_C2H2 experiment: Methyl-HT-SELEX Hamming distance: 1 cycle: 3
Length: 111
Pfam Domains:     20-42 C2H2-type zinc finger
    20-42 Zinc finger, C2H2 type
    20-37 C2H2-type zinc finger
    34-58 Zinc-finger double domain
    47-68 C2H2-type zinc finger
    48-70 C2H2-type zinc finger
    48-70 Zinc finger, C2H2 type
    62-85 Zinc-finger double domain
    76-96 C2H2-type zinc finger
    76-98 Zinc finger, C2H2 type
   76-100 C2H2-type zinc finger
Sequence: 
(in bold interface residues)		   1 LSPEKKPTRGRLPSKTKKEFVCKFCGRHFTKSYNLLIHERTHTDERPYTCDICHKAFRRQ   60
  61 DHLRDHRYIHSKEKPFKCQECGKGFCQSRTLAVHKTLHSQVKELKTSKIKC
Interface Residues: 10, 20, 30, 31, 32, 33, 34, 36, 37, 38, 44, 45, 58, 59, 60, 61, 62, 63, 64, 65, 66, 69, 86, 87, 88, 89, 90, 91, 93, 94, 97, 98
3D-footprint Homologues: 1ubd_C, 2kmk_A, 7y3l_A, 7n5w_A, 6jnm_A, 6ml4_A, 3uk3_C, 1tf3_A, 8cuc_F, 1g2f_F, 5kkq_D, 1tf6_A, 4x9j_A, 2gli_A, 5kl3_A, 5ei9_F, 2jpa_A, 1llm_D, 7w1m_H, 6blw_A, 5k5i_A, 6u9q_A, 2drp_D, 8h9h_G, 4m9v_C, 6e94_A, 2lt7_A, 8gh6_A, 7y3m_I, 7ysf_A, 6a57_A, 1yuj_A, 5yj3_D, 2wbs_A, 8gn3_A, 7txc_E, 5v3j_F, 1f2i_J, 5yel_A, 8ssq_A, 1le8_A
Binding Motifs: OSR1_2 yGCTACyGTk
OSR1_methyl_1 tGCTACYGTk
			
Related annotations: PaperBLAST

	
			


			

				

				
				
				
				

			

			

		

	
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