Transcription Factor
| Accessions: | O22176 (JASPAR 2024), T09826 (AthalianaCistrome v4_May2016) |
| Names: | Probable WRKY transcription factor 15, WRK15_ARATH, WRKY DNA-binding protein 15, AT2G23320, T09826;, WRKY15 |
| Organisms: | Arabidopsis thaliana |
| Libraries: | JASPAR 2024 1, AthalianaCistrome v4_May2016 2 1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] 2 O'Malley RC, Huang SS, Song L, Lewsey MG, Bartlett A, Nery JR, Galli M, Gallavotti A, Ecker JR. Cistrome and Epicistrome Features Shape the Regulatory DNA Landscape. Cell 165:1280-92 (2016). [Pubmed] |
| Uniprot: | O22176 |
| Notes: | ecotype:Col-0, experiment type: ampDAP-seq, experiment type: ampDAP-seq (methyl-cytosines removed by PCR), experiment type: DAP-seq, family:WRKY |
| Length: | 317 |
| Pfam Domains: | 190-237 Plant zinc cluster domain 241-298 WRKY DNA -binding domain |
| Sequence: (in bold interface residues) | 1 MAVELMTRNYISGVGADSFAVQEAAASGLKSIENFIGLMSRDSFNSDQPSSSSASASASA 60 61 AADLESARNTTADAAVSKFKRVISLLDRTRTGHARFRRAPVHVISPVLLQEEPKTTPFQS 120 121 PLPPPPQMIRKGSFSSSMKTIDFSSLSSVTTESDNQKKIHHHQRPSETAPFASQTQSLST 180 181 TVSSFSKSTKRKCNSENLLTGKCASASSSGRCHCSKKRKIKQRRIIRVPAISAKMSDVPP 240 241 DDYSWRKYGQKPIKGSPHPRGYYKCSSVRGCPARKHVERAADDSSMLIVTYEGDHNHSLS 300 301 AADLAGAAVADLILESS |
| Interface Residues: | 246, 247, 248, 250, 251, 262 |
| 3D-footprint Homologues: | 6j4e_B, 6j4f_F, 6j4g_B, 6ir8_A, 7z0u_A |
| Binding Motifs: | MA1076.1 arGTCAAmgs M0791 aaAAGTCAACg M0813 kcGTTGACTTTt MA1076.2 wwwwwrGTCAACGdtw MA1076.3 rGTCAACG |
| Binding Sites: | MA1076.3.10 / MA1076.3.11 / MA1076.3.13 / MA1076.3.2 / MA1076.3.4 / MA1076.3.5 / MA1076.3.8 / MA1076.3.9 MA1076.3.15 / MA1076.3.6 MA1076.3.20 MA1076.1.1 MA1076.1.10 MA1076.1.11 MA1076.1.12 MA1076.1.13 MA1076.1.14 MA1076.1.15 MA1076.1.16 MA1076.1.17 MA1076.1.18 MA1076.1.19 MA1076.1.2 MA1076.1.20 MA1076.1.3 MA1076.1.4 MA1076.1.5 MA1076.1.6 MA1076.1.7 MA1076.1.8 MA1076.1.9 MA1076.2.1 MA1076.2.10 MA1076.2.11 MA1076.2.12 MA1076.2.13 / MA1076.2.7 MA1076.2.14 / MA1076.2.8 MA1076.2.15 / MA1076.2.9 MA1076.2.16 MA1076.2.17 MA1076.2.18 MA1076.2.10 / MA1076.2.19 MA1076.2.2 MA1076.2.20 MA1076.2.2 / MA1076.2.3 MA1076.2.4 MA1076.2.5 MA1076.2.3 / MA1076.2.6 MA1076.2.4 / MA1076.2.7 MA1076.2.5 / MA1076.2.8 MA1076.2.6 / MA1076.2.9 MA1076.2.11 MA1076.2.12 MA1076.2.13 MA1076.2.14 MA1076.2.15 MA1076.2.16 MA1076.2.17 MA1076.2.18 MA1076.2.19 MA1076.2.20 MA1076.3.1 / MA1076.3.12 / MA1076.3.14 / MA1076.3.17 MA1076.3.16 MA1076.3.18 MA1076.3.19 MA1076.3.3 MA1076.3.7 |
| Publications: | Yu D, Chen C, Chen Z. 2001. Evidence for an important role of WRKY DNA binding proteins in the regulation of NPR1 gene expression. Plant Cell. 13:1527-40. [Pubmed] Weirauch MT, Yang A, Albu M, Cote AG, Montenegro-Montero A, Drewe P, Najafabadi HS, Lambert SA, Mann I, Cook K, Zheng H, Goity A, van Bakel H, Lozano JC, Galli M, Lewsey MG, Huang E, Mukherjee T, Chen X, Reece-Hoyes JS, Govindarajan S, Shaulsky G, et al. Determination and inference of eukaryotic transcription factor sequence specificity. Cell. 2014 Sep 11;158(6):1431-43. doi: 10.1016/j.cell.2014.08.009. [Pubmed] |
| Related annotations: | PaperBLAST |
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