Transcription Factor

Accessions: Q99941 (JASPAR 2024)
Names: Activating transcription factor 6 beta, ATF6-beta, ATF6B_HUMAN, cAMP response element-binding protein-related protein, cAMP-dependent transcription factor ATF-6 beta, cAMP-responsive element-binding protein-like 1, Creb-rp, Cyclic AMP-dependent transcription factor ATF-6 beta, Protein G13
Organisms: Homo sapiens
Libraries: JASPAR 2024 1
1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Uniprot: Q99941
Length: 703
Pfam Domains: 324-385 bZIP transcription factor
327-376 Basic region leucine zipper
Sequence:
(in bold interface residues)
1 MAELMLLSEIADPTRFFTDNLLSPEDWGLQNSTLYSGLDEVAEEQTQLFRCPEQDVPFDG 60
61 SSLDVGMDVSPSEPPWELLPIFPDLQVKSEPSSPCSSSSLSSESSRLSTEPSSEALGVGE 120
121 VLHVKTESLAPPLCLLGDDPTSSFETVQINVIPTSDDSSDVQTKIEPVSPCSSVNSEASL 180
181 LSADSSSQAFIGEEVLEVKTESLSPSGCLLWDVPAPSLGAVQISMGPSLDGSSGKALPTR 240
241 KPPLQPKPVVLTTVPMPSRAVPPSTTVLLQSLVQPPPVSPVVLIQGAIRVQPEGPAPSLP 300
301 RPERKSIVPAPMPGNSCPPEVDAKLLKRQQRMIKNRESACQSRRKKKEYLQGLEARLQAV 360
361 LADNQQLRRENAALRRRLEALLAENSELKLGSGNRKVVCIMVFLLFIAFNFGPVSISEPP 420
421 SAPISPRMNKGEPQPRRHLLGFSEQEPVQGVEPLQGSSQGPKEPQPSPTDQPSFSNLTAF 480
481 PGGAKELLLRDLDQLFLSSDCRHFNRTESLRLADELSGWVQRHQRGRRKIPQRAQERQKS 540
541 QPRKKSPPVKAVPIQPPGPPERDSVGQLQLYRHPDRSQPAFLDAIDRREDTFYVVSFRRD 600
601 HLLLPAISHNKTSRPKMSLVMPAMAPNETLSGRGAPGDYEEMMQIECEVMDTRVIHIKTS 660
661 TVPPSLRKQPSPTPGNATGGPLPVSAASQAHQASHQPLYLNHP
Interface Residues: 331, 335, 338, 339, 342, 343
3D-footprint Homologues: 7x5e_E, 2wt7_B, 5t01_B, 1dh3_C
Binding Motifs: UN0111.1 tGCCACGTCAyc
UN0110.1 grTGACGTCAyc
UN0112.1 yGCCACGTGGCA
UN0110.2 rTGACGTCAy
UN0111.2 tGCCACGTCAy
Related annotations: PaperBLAST

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