Transcription Factor

Accessions: O43298 (JASPAR 2024)
Names: ZBT43_HUMAN, Zinc finger and BTB domain-containing protein 22B, Zinc finger and BTB domain-containing protein 43, Zinc finger protein 297B, ZnF-x
Organisms: Homo sapiens
Libraries: JASPAR 2024 1
1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Uniprot: O43298
Length: 467
Pfam Domains: 23-125 BTB/POZ domain
375-394 C2H2-type zinc finger
389-410 Zinc-finger double domain
400-422 Zinc finger, C2H2 type
402-422 C2H2-type zinc finger
415-437 Zinc-finger double domain
428-450 C2H2-type zinc finger
Sequence:
(in bold interface residues)
1 MEPGTNSFRVEFPDFSSTILQKLNQQRQQGQLCDVSIVVQGHIFRAHKAVLAASSPYFCD 60
61 QVLLKNSRRIVLPDVMNPRVFENILLSSYTGRLVMPAPEIVSYLTAASFLQMWHVVDKCT 120
121 EVLEGNPTVLCQKLNHGSDHQSPSSSSYNGLVESFELGSGGHTDFPKAQELRDGENEEES 180
181 TKDELSSQLTEHEYLPSNSSTEHDRLSTEMASQDGEEGASDSAEFHYTRPMYSKPSIMAH 240
241 KRWIHVKPERLEQACEGMDVHATYDEHQVTESINTVQTEHTVQPSGVEEDFHIGEKKVEA 300
301 EFDEQADESNYDEQVDFYGSSMEEFSGERSDGNLIGHRQEAALAAGYSENIEMVTGIKEE 360
361 ASHLGFSATDKLYPCQCGKSFTHKSQRDRHMSMHLGLRPYGCGVCGKKFKMKHHLVGHMK 420
421 IHTGIKPYECNICAKRFMWRDSFHRHVTSCTKSYEAAKAEQNTTEAN
Interface Residues: 357, 358, 359, 362, 382, 383, 384, 385, 386, 387, 388, 389, 390, 393, 410, 411, 412, 413, 414, 415, 416, 417, 418, 436, 437, 438, 439, 440, 441, 442, 444, 445, 457, 458, 459
3D-footprint Homologues: 7eyi_G, 2i13_A, 5v3j_F, 1tf3_A, 7y3l_A, 7n5w_A, 6jnm_A, 6ml4_A, 6blw_A, 1tf6_A, 6u9q_A, 4x9j_A, 7txc_E, 6e94_A, 5kl3_A, 1ubd_C, 7ysf_A, 6wmi_A, 5ei9_F, 2jpa_A, 1mey_C, 2drp_D, 1g2f_F, 2kmk_A, 4m9v_C, 8h9h_G, 5kkq_D, 2lt7_A, 8ssq_A, 7w1m_H, 5und_A, 8ssu_A, 6a57_A, 5yel_A, 3uk3_C, 8cuc_F, 2gli_A, 8gn3_A, 1llm_D, 2wbs_A, 1f2i_J, 5yj3_D, 5k5i_A, 7y3m_I, 1hwt_C
Binding Motifs: UN0148.1 aGTGCCayawwrryAGCACt
UN0148.2 GTGCCayawwrryAGCAC
Related annotations: PaperBLAST

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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.