Transcription Factor

Accessions: P10035 (JASPAR 2024)
Names: HMH2_DROME
Organisms: Drosophila melanogaster
Libraries: JASPAR 2024 1
1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Length: 418
Pfam Domains: 298-352 Homeobox domain
Sequence:
(in bold interface residues)
1 MLLHESAASMEQSMPENLSTHMYGECEVNPTLAKCPDPVNVDHELPTKESCASTTIVSTS 60
61 PTSATSTTKVKLSFSVDRLLGSEPEESHRQSSSSPSTKSCCDGSILACCSFPHCFSQANA 120
121 ESRRFGHATLPPTFTPTSSHTYPFVGLDKLFPGPYMDYKSVLRPTPIRAAEHAAPTYPTL 180
181 ATNALLRFHQHQKQQHQQHHHHQHHPKHLHQQHKPPPHNSTTASALLAPLHSLTSLQLTQ 240
241 QQQRFLGKTPQQLLDIAPTSPAAAAAATSQNGAHGHGGGNGQGNASAGSNGKRKRSWSRA 300
301 VFSNLQRKGLEIQFQQQKYITKPDRRKLAARLNLTDAQVKVWFQNRRMKWRHTRENLKSG 360
361 QEKQPSAVPESGGVFKTSTPSGDGTPQEALDYSSDSCSSVDLSEQADEDDNIEINVVE
Interface Residues: 293, 294, 295, 296, 297, 298, 299, 337, 338, 340, 341, 344, 345, 348, 349, 352, 354, 361, 364
3D-footprint Homologues: 3cmy_A, 3d1n_M, 1nk2_P, 2lkx_A, 1puf_A, 6m3d_C, 7q3o_C, 6es3_K, 5jlw_D, 3lnq_A, 2ld5_A, 4xrs_G, 3a01_E, 2h1k_B, 1jgg_B, 5zfz_A, 3rkq_B, 5flv_I, 2hdd_A, 1au7_A, 5zjt_E, 4cyc_A, 2r5y_A, 1fjl_B, 7psx_B, 2hos_A, 1b72_A, 2xsd_C, 1ig7_A, 7xrc_C, 1e3o_C, 1le8_A, 1zq3_P, 1o4x_A, 1du0_A, 8g87_X, 1puf_B, 5hod_A, 6a8r_A, 4qtr_D
Binding Motifs: MA0448.1 tTwATdA
Binding Sites: MA0448.1.10
MA0448.1.4
MA0448.1.1
MA0448.1.11
MA0448.1.12
MA0448.1.13
MA0448.1.14
MA0448.1.15
MA0448.1.16
MA0448.1.17
MA0448.1.18
MA0448.1.19
MA0448.1.2
MA0448.1.20
MA0448.1.3
MA0448.1.5
MA0448.1.6
MA0448.1.7
MA0448.1.8
MA0448.1.9
Publications: Noyes M.B, Meng X, Wakabayashi A, Sinha S, Brodsky M.H, Wolfe S.A. A systematic characterization of factors that regulate Drosophila segmentation via a bacterial one-hybrid system. Nucleic acids research 36:2547-60 (2008). [Pubmed]
Related annotations: PaperBLAST

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These data are available AS IS and at your own risk. The EEAD/CSIC do not give any representation or warranty nor assume any liability or responsibility for the data nor the results posted (whether as to their accuracy, completeness, quality or otherwise). Access to these data is available free of charge for ordinary use in the course of research. Downloaded data have CC-BY-NC-SA license. FootprintDB is also available at RSAT::Plants, part of the INB/ELIXIR-ES resources portfolio.