Transcription Factor

						

			
Accessions: T165994_1.02 (CISBP 1.02)

			
Names: KLLA0D12672g, T165994_1.02;
Organisms: Kluyveromyces lactis, Saccharomyces cerevisiae
Libraries: CISBP 1.02 1
1 Weirauch MT, Yang A, Albu M, Cote AG, Montenegro-Montero A, Drewe P, Najafabadi HS, Lambert SA, Mann I, Cook K, Zheng H, Goity A, van Bakel H, Lozano JC, Galli M, Lewsey MG, Huang E, Mukherjee T, Chen X, Reece-Hoyes JS, Govindarajan S, Shaulsky G, et al. Determination and inference of eukaryotic transcription factor sequence specificity. Cell. 2014 Sep 11;158(6):1431-43. doi: 10.1016/j.cell.2014.08.009. [Pubmed]
Notes: family:Zinc cluster
Length: 865
Pfam Domains:    93-126 Fungal Zn(2)-Cys(6) binuclear cluster domain
  134-189 Gal4-like dimerisation domain
  389-610 Fungal specific transcription factor domain 
Sequence: 
(in bold interface residues)		   1 MGSRASNSPSFSSKAETLLPSEYKKNAVKKETIRNGKKRKLPDTESSDPEFASRRLIANE   60
  61 TGTDAVSNGNKNDSNANNNNNNNNKKSSEVMHQACDACRKKKWKCSKTVPTCTNCLKYNL  120
 121 DCVYSPQVVRTPLTRAHLTEMENRVAELEQFLKELFPVWDIDRLLQQKDTYRIRELLTMG  180
 181 STNTVPGLASNNIDSSLEQPVAFGTAQPAQSLSTDPAVQSQAYPMQPVPMTELQSITNLR  240
 241 HTPSLLDEQQMNTISTATLRNMYSSGNNNNNLGNISGLSPVTEAFFRWQEGETSIDNSYF  300
 301 GKGSILFWLNQLLSSEKIAGVTSKVGNDINTNNNNINHQKLPLILNNNITHNVSDITTTS  360
 361 TSSNKRAMSPLSANDSVYLAKRETISAYIDAYFKHYHALYPLVSKEMFFAQYNDQIKPEN  420
 421 VEIWHILLNAVLALGSWCSNSCSSHHTLYYQNALSYLSTAVLETGSTDLTIALILLTHYV  480
 481 QKMHKPNTAWSLIGLCSHMATSLGLHRDLPNSTIHDQQLRRVLWWTIYCTGCDLSLETGR  540
 541 PSLLPNLQAIDIPLPASSATIKEPSIYSSIIQESQWSQILQQKLSNNSYQQSAGECLSWF  600
 601 DSVQAFLDHWPTPSTEAELKALNETQLDWLPLVKFRPYWMFHCSLISLFSVFFEEDAPTD  660
 661 NNVIRCKELCLQLSSRNIFSVATFVRSYAFNSLSCWYATHYLVRSALVPLHFASRISPQH  720
 721 ALWETVKAQLLSAHEAMGILSQESSLAAKFDGILTKNYSEILQREGINKSQLMPPPTPLL  780
 781 QSTSFSDLLSLWSANAEDAPRVSNSQMPQSITITDSLLQSSTTQMRPPTTSGWPDTNNFL  840
 841 NPSTQQLFNTTTMDDVYNYIFDNDE
Interface Residues: 90, 99, 101, 102, 103, 104, 117, 118, 129, 130, 131, 132
3D-footprint Homologues: 6o19_A, 1f5e_P, 2er8_C, 2hap_D, 1pyi_A, 1zme_D, 1d66_B, 7uik_T, 3coq_A
Binding Motifs: M2452_1.02 hCGGAbyrmARwrwTCCGmkAv
			
Related annotations: PaperBLAST

	
			


			

				

				
				
				
				

			

			

		

	
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