Transcription Factor
| Accessions: | MBD2_HUMAN (HOCOMOCO 10) |
| Names: | Demethylase, DMTase, MBD2_HUMAN, Methyl-CpG-binding domain protein 2, Methyl-CpG-binding protein MBD2 |
| Organisms: | Homo sapiens |
| Libraries: | HOCOMOCO 10 1 1 Kulakovskiy IV, Vorontsov IE, Yevshin IS, Soboleva AV, Kasianov AS, Ashoor H, Ba-Alawi W, Bajic VB, Medvedeva YA, Kolpakov FA, Makeev VJ. HOCOMOCO: expansion and enhancement of the collection of transcription factor binding sites models. Nucleic Acids Res : (2016). [Pubmed] |
| Uniprot: | Q9UBB5 |
| Length: | 411 |
| Pfam Domains: | 147-215 Methyl-CpG binding domain 295-387 C-terminal domain of methyl-CpG binding protein 2 and 3 |
| Sequence: (in bold interface residues) | 1 MRAHPGGGRCCPEQEEGESAAGGSGAGGDSAIEQGGQGSALAPSPVSGVRREGARGGGRG 60 61 RGRWKQAGRGGGVCGRGRGRGRGRGRGRGRGRGRGRPPSGGSGLGGDGGGCGGGGSGGGG 120 121 APRREPVPFPSGSAGPGPRGPRATESGKRMDCPALPPGWKKEEVIRKSGLSAGKSDVYYF 180 181 SPSGKKFRSKPQLARYLGNTVDLSSFDFRTGKMMPSKLQKNKQRLRNDPLNQNKGKPDLN 240 241 TTLPIRQTASIFKQPVTKVTNHPSNKVKSDPQRMNEQPRQLFWEKRLQGLSASDVTEQII 300 301 KTMELPKGLQGVGPGSNDETLLSAVASALHTSSAPITGQVSAAVEKNPAVWLNTSQPLCK 360 361 AFIVTDEDIRKQEERVQQVRKKLEEALMADILSRAADTEEMDIEMDSGDEA |
| Interface Residues: | 166, 170, 171, 174, 176, 178, 186, 188 |
| 3D-footprint Homologues: | 6ogk_A, 3vxv_A, 6c1t_D, 2ky8_A, 6ceu_B, 2moe_A |
| Binding Motifs: | MBD2_HUMAN.H10MO.B|M01316 ssSkCCGGmgr |
| Related annotations: | PaperBLAST |
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