Transcription Factor
| Accessions: | 2v2t_B (3D-footprint 20231221) |
| Names: | DNA-binding factor KBF1, EBP-1, NF-kappa-B1 p84/NF-kappa-B1 p98, NFKB1_MOUSE, NUCLEAR FACTOR NF-KAPPA-B P105 SUBUNIT, Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 |
| Organisms: | Mus musculus |
| Libraries: | 3D-footprint 20231221 1 1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed] |
| Uniprot: | P25799 |
| Length: | 313 |
| Pfam Domains: | 5-203 Rel homology domain (RHD) |
| Sequence: (in bold interface residues) | 1 DGPYLQILEQPKQRGFRFRYVCEGPSHGGLPGASSEKNKKSYPQVKICNYVGPAKVIVQL 60 61 VTNGKNIHLHAHSLVGKHCEDGVCTVTAGPKDMVVGFANLGILHVTKKKVFETLEARMTE 120 121 ACIRGYNPGLLVHSDLAYLQAEGGGDRQLTDREKEIIRQAAVQQTKEMDLSVVRLMFTAF 180 181 LPDSTGSFTRRLEPVVSDAIYDSKAPNASNLKIVRMDRTAGCVTGGEEIYLLCDKVQKDD 240 241 IQIRFYEEEENGGVWEGFGDFSPTDVHRQFAIVFKTPKYKDVNITKPASVFVQLRRKSDL 300 301 ETSEPKPFLYYPE |
| Interface Residues: | 17, 19, 20, 22, 23, 25, 26, 27, 204, 206, 235, 268, 295, 296 |
| 3D-footprint Homologues: | 1a3q_A, 2o61_A, 1gji_A, 2ram_A, 1nfk_A, 7cli_B, 1p7h_L |
| Binding Motifs: | 2v2t_AB GGkAAnTcCC |
| Binding Sites: | 2v2t_C / 2v2t_D |
| Publications: | Moorthy A.K, Huang D.B, Wang V.Y, Vu D, Ghosh G. X-ray structure of a NF-kappaB p50/RelB/DNA complex reveals assembly of multiple dimers on tandem kappaB sites. Journal of molecular biology 373:723-34 (2007). [Pubmed] |
| Related annotations: | PaperBLAST |
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