Transcription Factor

Accessions: NHLH1_full (HumanTF 1.0)
Names: cDNA, FLJ94293, Homo sapiens nescient helix loop helix 1 (NHLH1, Nescient helix loop helix 1, NHLH1, Q5T203_HUMAN
Organisms: Homo sapiens
Libraries: HumanTF 1.0 1
1 Jolma A, Yan J, Whitington T, Toivonen J, Nitta KR, Rastas P, Morgunova E, Enge M, Taipale M, Wei G, Palin K, Vaquerizas JM, Vincentelli R, Luscombe NM, Hughes TR, Lemaire P, Ukkonen E, Kivioja T, Taipale J. DNA-Binding Specificities of Human Transcription Factors. Cell. 2013 Jan 17;152(1-2):327-39. [Pubmed]
Uniprot: Q5T203
Notes: Ensembl ID: ENSG00000171786; Full protein sequence; TF family: bHLH; Clone source: hORFeome
Length: 134
Pfam Domains: 77-127 Helix-loop-helix DNA-binding domain
Sequence:
(in bold interface residues)
1 MMLNSDTMELDLPPTHSETESGFSDCGGGAGPDGAGPGGPGGGQARGPEPGEPGRKDLQH 60
61 LSREERRRRRRATAKYRTAHATRERIRVEAFNLAFAELRKLLPTLPPDKKLSKIEILRLA 120
121 ICYISYLNHVLDV*
Interface Residues: 77, 81, 83, 84, 87
3D-footprint Homologues: 7z5k_B, 8osb_B, 8osl_P
Binding Motifs: NHLH1_full cGCAGCTGCk
Publications: Jolma A, Yan J, Whitington T, Toivonen J, Nitta KR, Rastas P, Morgunova E, Enge M, Taipale M, Wei G, Palin K, Vaquerizas JM, Vincentelli R, Luscombe NM, Hughes TR, Lemaire P, Ukkonen E, Kivioja T, Taipale J. DNA-Binding Specificities of Human Transcription Factors. Cell. 2013 Jan 17;152(1-2):327-39. [Pubmed]
Related annotations: PaperBLAST

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