Transcription Factor

						

			
Accessions: 5edn_B (3D-footprint 20231221), 5edn_J (3D-footprint 20231221), 5eea_B (3D-footprint 20231221), 5eg0_B (3D-footprint 20231221)

			
Names: Homeobox protein Hox-B13, HXB13_HUMAN
Organisms: Homo sapiens
Libraries: 3D-footprint 20231221 1
1 Contreras-Moreira B. 3D-footprint: a database for the structural analysis of protein-DNA complexes. Nucleic acids research 38:D91-7 (2010). [Pubmed]
Uniprot: Q92826
Length: 61
Pfam Domains:      1-57 Homeobox domain
Sequence: 
(in bold interface residues)		   1 RKKRIPYSKGQLRELEREYAANKFITKDKRRKISAATSLSERQITIWFQNRRVKEKKVLA   60
  61 K
Interface Residues: 1, 2, 3, 4, 12, 28, 30, 42, 43, 45, 46, 49, 50, 53, 54, 57
3D-footprint Homologues: 1fjl_B, 5zfz_A, 1ig7_A, 2h1k_B, 1puf_A, 3cmy_A, 6a8r_A, 1nk2_P, 1zq3_P, 2lkx_A, 7q3o_C, 6es3_K, 2ld5_A, 3lnq_A, 2hos_A, 4xrs_G, 1b72_A, 3rkq_B, 5flv_I, 3a01_E, 5zjt_E, 4cyc_A, 1jgg_B, 2hdd_A, 7psx_B, 2r5y_A, 6m3d_C, 1au7_A, 5jlw_D, 6vu3_A, 6vz3_A, 2xsd_C, 1le8_A, 7xrc_C, 1e3o_C, 1o4x_A, 6fqp_B, 1le8_B, 1du0_A, 6fqq_E, 5hod_A, 1mnm_C, 4qtr_D, 1puf_B, 1k61_B
Binding Motifs: 5edn_AJ ATAAAnnnCnnTTnnnnTTTAT
5edn_BG gnnnnnGTAAAnnnnnGnnnnnntnaCTAG
5edn_J TnGTAAA
5eea_B tTTaTTGnG
5eg0_AB TnGTAAAnnTGTCA
5eg0_B tngTAAA
Binding Sites: 5eea_D
5eea_E
5eg0_D
5eg0_E
5edn_K
5edn_L
			
Publications: Morgunova E, Yin Y, Das PK, Jolma A, Zhu F, Popov A, Xu Y, Nilsson L, Taipale J. Two distinct DNA sequences recognized by transcription factors represent enthalpy and entropy optima. Elife : (2018). [Pubmed]
Related annotations: PaperBLAST

	
			


			

				

				
				
				
				

			

			

		

	
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