Transcription Factor

Accessions: Q96JL9 (JASPAR 2024)
Names: ZN333_HUMAN
Organisms: Homo sapiens
Libraries: JASPAR 2024 1
1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed]
Length: 665
Pfam Domains: 4-41 KRAB box
203-242 KRAB box
366-388 C2H2-type zinc finger
366-388 C2H2-type zinc finger
366-388 Zinc finger, C2H2 type
381-405 Zinc-finger double domain
394-416 C2H2-type zinc finger
394-416 Zinc finger, C2H2 type
396-416 C2H2-type zinc finger
408-433 Zinc-finger double domain
422-444 C2H2-type zinc finger
422-444 C2H2-type zinc finger
422-444 Zinc finger, C2H2 type
437-460 Zinc-finger double domain
449-468 C2H2-type zinc finger
450-472 Zinc finger, C2H2 type
450-472 C2H2-type zinc finger
464-487 Zinc-finger double domain
478-500 Zinc finger, C2H2 type
478-500 C2H2-type zinc finger
478-500 C2H2-type zinc finger
492-517 Zinc-finger double domain
505-526 C2H2-type zinc finger
506-528 Zinc finger, C2H2 type
506-528 C2H2-type zinc finger
520-541 Zinc-finger double domain
533-556 C2H2-type zinc finger
534-556 Zinc finger, C2H2 type
549-572 Zinc-finger double domain
562-584 C2H2-type zinc finger
562-584 C2H2-type zinc finger
562-584 Zinc finger, C2H2 type
576-600 Zinc-finger double domain
590-612 C2H2-type zinc finger
590-612 Zinc finger, C2H2 type
605-629 Zinc-finger double domain
618-640 C2H2-type zinc finger
618-640 C2H2-type zinc finger
618-640 Zinc finger, C2H2 type
Sequence:
(in bold interface residues)
1 MESVTFEDVAVEFIQEWALLDSARRSLCKYRMLDQCRTLASRGTPPCKPSCVSQLGQRAE 60
61 PKATERGILRATGVAWESQLKPEELPSMQDLLEEASSRDMQMGPGLFLRMQLVPSIEERE 120
121 TPLTREDRPALQEPPWSLGCTGLKAAMQIQRVVIPVPTLGHRNPWVARDSAVPARDPAWL 180
181 QEDKVEEEAMAPGLPTACSQEPVTFADVAVVFTPEEWVFLDSTQRSLYRDVMLENYRNLA 240
241 SVADQLCKPNALSYLEERGEQWTTDRGVLSDTCAEPQCQPQEAIPSQDTFTEILSIDVKG 300
301 EQPQPGEKLYKYNELEKPFNSIEPLFQYQRIHAGEASCECQEIRNSFFQSAHLIVPEKIR 360
361 SGDKSYACNKCEKSFRYSSDLIRHEKTHTAEKCFDCQECGQAFKYSSNLRRHMRTHTGEK 420
421 PFECSQCGKTFTRNFNLILHQRNHTGEKPYECKDCGKAFNQPSSLRSHVRTHTGEKPFEC 480
481 SQCGKAFREHSSLKTHLRTHTREKPYECNQCGKPFRTSTHLNVHKRIHTGEKLYECATCG 540
541 QVLSRLSTLKSHMRTHTGEKPYVCQECGRAFSEPSSLRKHARTHSGKKPYACQECGRAFG 600
601 QSSHLIVHVRTHSAGRPYQCNQCEKAFRHSSSLTVHKRTHVGRETIRNGSLPLSMSHPYC 660
661 GPLAN
Interface Residues: 377, 379, 383, 404, 405, 406, 407, 408, 410, 411, 432, 433, 434, 435, 436, 438, 439, 441, 442, 445, 460, 461, 462, 463, 464, 466, 467, 468, 488, 489, 490, 491, 492, 493, 494, 495, 496, 499, 516, 517, 518, 519, 520, 521, 522, 523, 525, 529, 534, 545, 546, 547, 548, 549, 551, 554, 572, 573, 574, 575, 576, 578, 579, 585, 599, 601, 602, 603, 604, 606, 607, 611, 628, 629, 630, 631, 632, 635
3D-footprint Homologues: 7w1m_H, 7ysf_A, 1ubd_C, 7n5w_A, 7txc_E, 5k5l_F, 8gn3_A, 8h9h_G, 2lt7_A, 6jnm_A, 3uk3_C, 5kl3_A, 5v3j_F, 8ssq_A, 6blw_A, 6u9q_A, 4x9j_A, 8ssu_A, 5kkq_D, 6a57_A, 5yel_A, 2jpa_A, 1tf3_A, 8cuc_F, 7y3l_A, 1g2f_F, 1llm_D, 6ml4_A, 1tf6_A, 4m9v_C, 7y3m_I, 6e94_A, 5k5i_A, 5yj3_D, 2gli_A, 5ei9_F, 2kmk_A, 2drp_D, 1f2i_J, 2wbs_A
Binding Motifs: UN0609.1 sTGGAGsmG
Related annotations: PaperBLAST

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