Transcription Factor
| Accessions: | P28700 (JASPAR 2024) |
| Names: | Nuclear receptor subfamily 2 group B member 1, Retinoic acid receptor RXR-alpha, Retinoid X receptor alpha, RXRA_MOUSE |
| Organisms: | Mus musculus |
| Libraries: | JASPAR 2024 1 1 Rauluseviciute I, Riudavets-Puig R, Blanc-Mathieu R, Castro-Mondragon JA, Ferenc K, Kumar V, Lemma RB, Lucas J, Cheneby J, Baranasic D, Khan A, Fornes O, Gundersen S, Johansen M, Hovig E, Lenhard B, Sandelin A, Wasserman WW, Parcy F, Mathelier A. JASPAR 2024: 20th anniversary of the open-access database of transcription factor binding profiles. Nucleic Acids Res : (2023). [Pubmed] |
| Uniprot: | P28700 |
| Length: | |
| Binding Motifs: | MA0065.2 strGGgcArAGGkcA PB0057.1 tshykTGACCCCdyrmt PB0161.1 kcrcrwAGktyrtwmk MA0512.2 grGGTCAAAGGTCA MA0494.1 TGaCCtvrrGTrACCyykg MA0512.1 CArAGKTCAgd |
| Binding Sites: | MA0065.2.1 MA0065.2.10 MA0065.2.11 MA0065.2.12 MA0065.2.13 MA0065.2.14 MA0065.2.15 MA0065.2.16 MA0065.2.17 MA0065.2.18 MA0065.2.19 MA0065.2.2 MA0065.2.20 MA0065.2.3 MA0065.2.4 MA0065.2.5 MA0065.2.6 MA0065.2.7 MA0065.2.8 MA0065.2.9 MA0494.1.1 MA0494.1.10 MA0494.1.11 MA0494.1.12 MA0494.1.13 MA0494.1.14 MA0494.1.15 MA0494.1.16 MA0494.1.17 MA0494.1.18 MA0494.1.19 MA0494.1.2 MA0494.1.20 MA0494.1.3 MA0494.1.4 MA0494.1.5 MA0494.1.6 MA0494.1.7 MA0494.1.8 MA0494.1.9 MA0512.1.1 MA0512.1.10 MA0512.1.11 MA0512.1.12 MA0512.1.13 MA0512.1.14 MA0512.1.15 MA0512.1.16 MA0512.1.17 MA0512.1.18 MA0512.1.19 MA0512.1.2 MA0512.1.20 MA0512.1.3 MA0512.1.4 MA0512.1.5 MA0512.1.6 MA0512.1.7 MA0512.1.8 MA0512.1.9 |
| Publications: | Zhang X.-K., Lehmann J., Hoffmann B., Dawson M. I., Cameron J., Graupner G., Hermann T., Tran P., Pfahl M. Homodimer formation of retinoid X receptor induced by 9-cis retinoic acid. Nature 358:587-591 (1992). [Pubmed] Badis G, Berger M.F, Philippakis A.A, Talukder S, Gehrke A.R, Jaeger S.A, Chan E.T, Metzler G, Vedenko A, Chen X, Kuznetsov H, Wang C.F, Coburn D, Newburger D.E, Morris Q, Hughes T.R, Bulyk M.L. Diversity and complexity in DNA recognition by transcription factors. Science (New York, N.Y.) 324:1720-3 (2009). [Pubmed] Nielsen R, Pedersen T.A, Hagenbeek D, Moulos P, Siersbaek R, Megens E, Denissov S, Børgesen M, Francoijs K.J, Mandrup S, Stunnenberg H.G. Genome-wide profiling of PPARgamma:RXR and RNA polymerase II occupancy reveals temporal activation of distinct metabolic pathways and changes in RXR dimer composition during adipogenesis. Genes & development 22:2953-67 (2008). [Pubmed] Zhao Q, Chasse S.A, Devarakonda S, Sierk M.L, Ahvazi B, Rastinejad F. Structural basis of RXR-DNA interactions. Journal of molecular biology 296:509-20 (2000). [Pubmed] Shen Q, Bai Y, Chang K.C, Wang Y, Burris T.P, Freedman L.P, Thompson C.C, Nagpal S. Liver X receptor-retinoid X receptor (LXR-RXR) heterodimer cistrome reveals coordination of LXR and AP1 signaling in keratinocytes. The Journal of biological chemistry 286:14554-63 (2011). [Pubmed] |
| Related annotations: | PaperBLAST |
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